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Circadian clocks and insulin resistance
Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a
major cause of morbidity and mortality. The circadian timing system consists of a central …
major cause of morbidity and mortality. The circadian timing system consists of a central …
Developmental trajectories of early life stress and trauma: a narrative review on neurobiological aspects beyond stress system dysregulation
Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …
Mental health in elite athletes: International Olympic Committee consensus statement (2019)
CL Reardon, B Hainline, CM Aron, D Baron… - British journal of sports …, 2019 - bjsm.bmj.com
Mental health symptoms and disorders are common among elite athletes, may have sport
related manifestations within this population and impair performance. Mental health cannot …
related manifestations within this population and impair performance. Mental health cannot …
Circadian misalignment increases cardiovascular disease risk factors in humans
Shift work is a risk factor for hypertension, inflammation, and cardiovascular disease. This
increased risk cannot be fully explained by classic risk factors. One of the key features of …
increased risk cannot be fully explained by classic risk factors. One of the key features of …
Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans
CJ Morris, JN Yang, JI Garcia, S Myers, I Bozzi… - Proceedings of the …, 2015 - pnas.org
Glucose tolerance is lower in the evening and at night than in the morning. However, the
relative contribution of the circadian system vs. the behavioral cycle (including the …
relative contribution of the circadian system vs. the behavioral cycle (including the …
Circadian system and glucose metabolism: implications for physiology and disease
The circadian system serves one of the most fundamental properties present in nearly all
organisms: it generates 24-h rhythms in behavioral and physiological processes and …
organisms: it generates 24-h rhythms in behavioral and physiological processes and …
Working Time Society consensus statements: Evidence-based effects of shift work on physical and mental health
Potential effects of shift work on health are probably related to the misalignment between the
light-dark cycle and the human activity-rest cycle. Light exposure at night mediates these …
light-dark cycle and the human activity-rest cycle. Light exposure at night mediates these …
Circadian clock control of endocrine factors
Organisms experience dramatic fluctuations in demands and stresses over the course of the
day. In order to maintain biological processes within physiological boundaries, mechanisms …
day. In order to maintain biological processes within physiological boundaries, mechanisms …
Evening chronotype is associated with metabolic disorders and body composition in middle-aged adults
Context: Chronotype is a trait determining individual circadian preference in behavioral and
biological rhythm relative to external light-dark cycle. However, little is known about the …
biological rhythm relative to external light-dark cycle. However, little is known about the …
The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms
Modern lifestyle has profoundly modified human sleep habits. Sleep duration has shortened
over recent decades from 8 to 6.5 hours resulting in chronic sleep deprivation. Additionally …
over recent decades from 8 to 6.5 hours resulting in chronic sleep deprivation. Additionally …