Circadian clocks and insulin resistance

DJ Stenvers, FAJL Scheer, P Schrauwen… - Nature reviews …, 2019 - nature.com
Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a
major cause of morbidity and mortality. The circadian timing system consists of a central …

Developmental trajectories of early life stress and trauma: a narrative review on neurobiological aspects beyond stress system dysregulation

A Agorastos, P Pervanidou, GP Chrousos… - Frontiers in …, 2019 - frontiersin.org
Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …

Mental health in elite athletes: International Olympic Committee consensus statement (2019)

CL Reardon, B Hainline, CM Aron, D Baron… - British journal of sports …, 2019 - bjsm.bmj.com
Mental health symptoms and disorders are common among elite athletes, may have sport
related manifestations within this population and impair performance. Mental health cannot …

Circadian misalignment increases cardiovascular disease risk factors in humans

CJ Morris, TE Purvis, K Hu, FAJL Scheer - Proceedings of the National …, 2016 - pnas.org
Shift work is a risk factor for hypertension, inflammation, and cardiovascular disease. This
increased risk cannot be fully explained by classic risk factors. One of the key features of …

Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans

CJ Morris, JN Yang, JI Garcia, S Myers, I Bozzi… - Proceedings of the …, 2015 - pnas.org
Glucose tolerance is lower in the evening and at night than in the morning. However, the
relative contribution of the circadian system vs. the behavioral cycle (including the …

Circadian system and glucose metabolism: implications for physiology and disease

J Qian, FAJL Scheer - Trends in Endocrinology & Metabolism, 2016 - cell.com
The circadian system serves one of the most fundamental properties present in nearly all
organisms: it generates 24-h rhythms in behavioral and physiological processes and …

Working Time Society consensus statements: Evidence-based effects of shift work on physical and mental health

CRC Moreno, EC Marqueze, C Sargent… - Industrial …, 2019 - jstage.jst.go.jp
Potential effects of shift work on health are probably related to the misalignment between the
light-dark cycle and the human activity-rest cycle. Light exposure at night mediates these …

Circadian clock control of endocrine factors

KL Gamble, R Berry, SJ Frank, ME Young - Nature Reviews …, 2014 - nature.com
Organisms experience dramatic fluctuations in demands and stresses over the course of the
day. In order to maintain biological processes within physiological boundaries, mechanisms …

Evening chronotype is associated with metabolic disorders and body composition in middle-aged adults

JH Yu, CH Yun, JH Ahn, S Suh, HJ Cho… - The Journal of …, 2015 - academic.oup.com
Context: Chronotype is a trait determining individual circadian preference in behavioral and
biological rhythm relative to external light-dark cycle. However, little is known about the …

The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms

A Briançon-Marjollet, M Weiszenstein, M Henri… - Diabetology & metabolic …, 2015 - Springer
Modern lifestyle has profoundly modified human sleep habits. Sleep duration has shortened
over recent decades from 8 to 6.5 hours resulting in chronic sleep deprivation. Additionally …