Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application
Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …
Clinical development of metal complexes as photosensitizers for photodynamic therapy of cancer
J Karges - Angewandte chemie international edition, 2022 - Wiley Online Library
Cancer has emerged over the last decades as one of the deadliest diseases in the world.
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …
Recent advances in noble metal complex based photodynamic therapy
Photodynamic therapy (PDT) utilizes light-activated photosensitizers (PSs) to generate toxic
species for therapeutics. It has become an emerging solution for cancer treatment because …
species for therapeutics. It has become an emerging solution for cancer treatment because …
Nanobodies: next generation of cancer diagnostics and therapeutics
The development of targeted medicine has greatly expanded treatment options and spurred
new research avenues in cancer therapeutics, with monoclonal antibodies (mAbs) emerging …
new research avenues in cancer therapeutics, with monoclonal antibodies (mAbs) emerging …
Engineered bacteria labeled with iridium (III) photosensitizers for enhanced photodynamic immunotherapy of solid tumors
W Lin, Y Liu, J Wang, Z Zhao, K Lu, H Meng… - Angewandte …, 2023 - Wiley Online Library
Despite metal‐based photosensitizers showing great potential in photodynamic therapy for
tumor treatment, the application of the photosensitizers is intrinsically limited by their poor …
tumor treatment, the application of the photosensitizers is intrinsically limited by their poor …
Rationally designed long-wavelength absorbing Ru (II) polypyridyl complexes as photosensitizers for photodynamic therapy
J Karges, F Heinemann, M Jakubaszek… - Journal of the …, 2020 - ACS Publications
The utilization of photodynamic therapy (PDT) for the treatment of various types of cancer
has gained increasing attention over the last decades. Despite the clinical success of …
has gained increasing attention over the last decades. Despite the clinical success of …
Encapsulation of Ru (II) polypyridine complexes for tumor-targeted anticancer therapy
J Karges - BME frontiers, 2023 - spj.science.org
Ru (II) polypyridine complexes have attracted much attention as anticancer agents because
of their unique photophysical, photochemical, and biological properties. Despite their …
of their unique photophysical, photochemical, and biological properties. Despite their …
Recent progress in metal complexes functionalized nanomaterials for photodynamic therapy
F Wei, Z Chen, XC Shen, L Ji, H Chao - Chemical Communications, 2023 - pubs.rsc.org
Metal complexes have shown promise as photosensitizers for cancer diagnosis and
therapeutics. However, the vast majority of metal photosensitizers are not ideal and …
therapeutics. However, the vast majority of metal photosensitizers are not ideal and …
Nanobodies as molecular imaging probes
Camelidae derived single-domain antibodies (sdAbs), commonly known as nanobodies
(Nbs), are the smallest antibody fragments with full antigen-binding capacity. Owing to their …
(Nbs), are the smallest antibody fragments with full antigen-binding capacity. Owing to their …
EGFR-targeted photodynamic therapy
L Ulfo, PE Costantini, M Di Giosia, A Danielli… - Pharmaceutics, 2022 - mdpi.com
The epidermal growth factor receptor (EGFR) plays a pivotal role in the proliferation and
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …