Immunotherapy is regarded as the most promising treatment for cancers. Various cancer
immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies …

COVID-19 is a contagious viral disease caused by SARS-CoV-2 that led to an ongoing
pandemic with massive global health and socioeconomic consequences. The disease is …

The last decade has been somewhat of a renaissance period for the field of macrophage
biology. This renewed interest, combined with the advent of new technologies and …

Kupffer cells (KCs) are liver-resident macrophages that self-renew by proliferation in the
adult independently from monocytes. However, how they are maintained during non …

Macrophages are critical for innate immune defense and also control organ homeostasis in
a tissue-specific manner. They provide a fitting model to study the impact of ontogeny and …

Tissue-resident macrophage populations constitute a mosaic of phenotypes, yet how their
metabolic states link to the range of phenotypes and functions in vivo is still poorly defined …

Distinct macrophage populations throughout the body display highly heterogeneous
transcriptional and epigenetic programs. Recent research has highlighted that these profiles …

The current paradigm in macrophage biology is that some tissues mainly contain
macrophages from embryonic origin, such as microglia in the brain, whereas other tissues …

Macrophages are distributed in tissues throughout the body and contribute to both
homeostasis and disease. Recently, it has become evident that most adult tissue …

Macrophages are immune cells of haematopoietic origin that provide crucial innate immune
defence and have tissue-specific functions in the regulation and maintenance of organ …