Review of recent advances in lipid analysis of biological samples via ambient ionization mass spectrometry

H Lu, H Zhang, S Xu, L Li - Metabolites, 2021 - mdpi.com
The rapid and direct structural characterization of lipids proves to be critical for studying the
functional roles of lipids in many biological processes. Among numerous analytical …

Ambient mass spectrometry for the molecular diagnosis of lung cancer

H Lu, H Zhang, Y Wei, H Chen - Analyst, 2020 - pubs.rsc.org
Lung cancer is one of the most common malignancies and the leading cause of cancer-
related death worldwide. Among the technologies suitable for the rapid and accurate …

Liver metabolic dysregulation induced by polypropylene nano-and microplastics in nile tilapia using internal extractive electrospray ionization mass spectrometry

X Wu, M Li, S Yang, J Dong, W Pan, Y Ning… - Analytical …, 2023 - ACS Publications
Understanding the metabolic disorders induced by nano-and microplastics in aquatic
organisms at the molecular level could help us understand the potential toxicity of nano-and …

Metabolic-dysregulation-based iEESI-MS reveals potential biomarkers associated with early-stage and progressive colorectal cancer

R Zheng, R Su, F **ng, Q Li, B Liu, D Wang… - Analytical …, 2022 - ACS Publications
The application of rapid and accurate diagnostic methods can improve colorectal cancer
(CRC) survival rates dramatically. Here, we used a non-targeted metabolic analysis strategy …

Direct differentiation of whole blood for forensic serology analysis by thread spray mass spectrometry

S Jackson, BS Frey, MN Bates, DJ Swiner… - Analyst, 2020 - pubs.rsc.org
Direct analysis of whole blood on bloodstained textiles is achieved with thread spray mass
spectrometry (MS). This capability satisfies investigators' first priority in crime scene …

[HTML][HTML] Breast cancer diagnosis based on lipid profiling by probe electrospray ionization mass spectrometry

T Iwano, K Yoshimura, S Inoue, T Odate… - The British Journal of …, 2020 - ncbi.nlm.nih.gov
Probe electrospray ionization mass spectrometry (PESI‐MS) is an ambient ionization‐based
mass spectrometry method that surpasses the original electrospray ionization technique in …

Selective detection of phospholipids in human blood plasma and single cells for cancer differentiation using dispersed solid-phase microextraction combined with …

H Zhang, H Lu, K Huang, J Li, F Wei, A Liu, K Chingin… - Analyst, 2020 - pubs.rsc.org
Phospholipids in microvolume biofluid samples (≤ 0.5 μL), including human plasma and
single cells, were selectively captured by dispersed magnetic Fe3O4@ TiO2 nanocomposite …

Machine Learning-Based Integrated Multiomics Characterization of Colorectal Cancer Reveals Distinctive Metabolic Signatures

R Zheng, R Su, Y Fan, F **ng, K Huang, F Yan… - Analytical …, 2024 - ACS Publications
The metabolic signature identification of colorectal cancer is critical for its early diagnosis
and therapeutic approaches that will significantly block cancer progression and improve …

Ambient electric arc ionization for versatile sample analysis using mass spectrometry

Y Gao, Y Li, B Zhan, Q He, H Zhu, W Chen, Q Yin… - Analyst, 2021 - pubs.rsc.org
A novel, convenient ambient electric arc ionization (AEAI) device was developed as a mass
spectrometry ion source for versatile sample analysis. AEAI could be considered as a soft …

Direct quantitative profiling of amino acids in tissues for the assessment of lung cancer

H Lu, Y Li, H Zhang, K Chingin, Y Wei, K Huang… - Talanta, 2021 - Elsevier
Direct molecular analysis of tissue samples is a promising approach to increase the
accuracy, speed and molecular specificity of cancer diagnosis. Herein, alterations of amino …