Tumor targeting via EPR: Strategies to enhance patient responses

SK Golombek, JN May, B Theek, L Appold… - Advanced drug delivery …, 2018 - Elsevier
The tumor accumulation of nanomedicines relies on the enhanced permeability and
retention (EPR) effect. In the last 5–10 years, it has been increasingly recognized that there …

Ultrasound-mediated nano drug delivery for treating cancer: Fundamental physics to future directions

FM Kashkooli, A Jakhmola, TK Hornsby… - Journal of Controlled …, 2023 - Elsevier
The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …

Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come

P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - Elsevier
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

E Pérez-Herrero, A Fernández-Medarde - European journal of …, 2015 - Elsevier
Cancer is the second worldwide cause of death, exceeded only by cardiovascular diseases.
It is characterized by uncontrolled cell proliferation and an absence of cell death that, except …

Image-guided tumor ablation: standardization of terminology and reporting criteria—a 10-year update

M Ahmed, L Solbiati, CL Brace, DJ Breen… - Radiology, 2014 - pubs.rsna.org
Image-guided tumor ablation has become a well-established hallmark of local cancer
therapy. The breadth of options available in this growing field increases the need for …

[HTML][HTML] Hyperthermia and smart drug delivery systems for solid tumor therapy

ALB Seynhaeve, M Amin, D Haemmerich… - Advanced Drug Delivery …, 2020 - Elsevier
Chemotherapy is a cornerstone of cancer therapy. Irrespective of the administered drug, it is
crucial that adequate drug amounts reach all cancer cells. To achieve this, drugs first need …

Non‐invasive thermal therapy for tissue engineering and regenerative medicine

L Li, X Zhang, J Zhou, L Zhang, J Xue, W Tao - Small, 2022 - Wiley Online Library
Owing to the development of nanotechnology and noninvasive treatment, thermal therapy in
combination with external stimuli has been applied for tissue engineering and regenerative …

Thermosensitive liposomal drug delivery systems: state of the art review

B Kneidl, M Peller, G Winter, LH Lindner… - International journal of …, 2014 - Taylor & Francis
Thermosensitive liposomes are a promising tool for external targeting of drugs to solid
tumors when used in combination with local hyperthermia or high intensity focused …

Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open …

PC Lyon, MD Gray, C Mannaris, LK Folkes… - The Lancet …, 2018 - thelancet.com
Background Previous preclinical research has shown that extracorporeal devices can be
used to enhance the delivery and distribution of systemically administered anticancer drugs …

Lipid-based nanoparticle technologies for liver targeting

R Böttger, G Pauli, PH Chao, NAL Fayez… - Advanced drug delivery …, 2020 - Elsevier
Liver diseases such as hepatitis, cirrhosis, and hepatocellular carcinoma are global health
problems accounting for approximately 800 million cases and over 2 million deaths per year …