Even though, nowadays, cancer is one of the leading causes of death, too little is known
about the behavior of this disease due to its unpredictability from one patient to another …

Cancer therapy optimization is an issue that can be solved using the control engineering
approach. An optimal therapy generation algorithm is presented and tested using a tractable …

Personalized therapy based on mathematical foundations is a promising method for treating
various types of cancer. By identifying the parameters of mathematical equations, we could …

In the field of medical research, therapy optimization is a crucial area that deserves
significant attention. In chemotherapy, tumor modeling plays an essential role in describing …

The application of the achievements of mathematics and informatics greatly helped the
development of medicine. Designing personalized therapies using different algorithms is …

Therapy optimization and personalization in cancer treatment requires reliable mathematical
models. A key issue in personalization is the identification of the model parameters. We …

A nonlinear Moving Horizon Estimator (MHE) was developed which can estimate the time-
varying parameters of a tumor growth model under chemotherapeutic treatment. We …

Cyber-medical systems provides lots of possibilities that help doctors plan more effective
treatments. A reliable mathematical model that can be customized is essential for therapy …

Personalization of chemotherapy requires a mathematical model tailored to the patient. The
tailoring requires the knowledge of the parameters specific to the patient, however, these …

In this paper we treat the problem of cancer control by chemotherapy, through general
model in ordinary differential equation form of tumor dynamics. The model is augmented by …