Chronic inflammation is a component of many disease conditions that affect a large group of
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Antisense oligonucleotides (ASOs) are promising tools for gene silencing and have been
exploited as therapeutics for human disease. However, delivery of therapeutic ASOs to …

Discovered in the late 1980s as an extracellular vesicle of endosomal origin secreted from
reticulocytes, exosomes recently gained scientific attention due to its role in intercellular …

Atherosclerosis is a chronic progressive disease that involves damage to the intima,
inflammatory cell recruitment and the accumulation of lipids followed by calcification and …

Cardiovascular disease is a leading cause of death worldwide. The underlying mechanisms
of most cardiovascular disorders involve innate and adaptive immune responses, and …

Obesity is characterized by an increase in body weight associated with an exaggerated
enlargement of the adipose tissue. Obesity has serious negative effects because it is …

Emerging evidence highlights the relevance of extracellular vesicles (EVs) in modulating
human diseases including but not limited to cancer, inflammation, and neurological …

Cardiovascular disease (CVD) has overtaken infectious illnesses as the leading cause of
mortality and disability worldwide. The pathology that underpins CVD is atherosclerosis …

Mitochondria are organelles present in almost all eukaryotic cells, where they represent the
main site of energy production. Mitochondria are involved in several important cell …