Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories

T Hainmueller, M Bartos - Nature Reviews Neuroscience, 2020 - nature.com
The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

[HTML][HTML] Hippocampal GABAergic interneurons and memory

A Tzilivaki, JJ Tukker, N Maier, P Poirazi, RP Sammons… - Neuron, 2023 - cell.com
One of the most captivating questions in neuroscience revolves around the brain's ability to
efficiently and durably capture and store information. It must process continuous input from …

Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Parallel emergence of stable and dynamic memory engrams in the hippocampus

T Hainmueller, M Bartos - Nature, 2018 - nature.com
During our daily life, we depend on memories of past experiences to plan future behaviour.
These memories are represented by the activity of specific neuronal groups or 'engrams' …

Gamma oscillation plasticity is mediated via parvalbumin interneurons

MD Hadler, A Tzilivaki, D Schmitz, H Alle… - Science …, 2024 - science.org
Understanding the plasticity of neuronal networks is an emerging field of (patho-)
physiological research, yet the underlying cellular mechanisms remain poorly understood …

Subfield-specific interneuron circuits govern the hippocampal response to novelty in male mice

T Hainmueller, A Cazala, LW Huang… - Nature …, 2024 - nature.com
The hippocampus is the brain's center for episodic memories. Its subregions, the dentate
gyrus and CA1-3, are differentially involved in memory encoding and recall. Hippocampal …

NMDA receptor-independent LTP in mammalian nervous system

KA Alkadhi - Progress in Neurobiology, 2021 - Elsevier
Long-term potentiation (LTP) of synaptic transmission is a form of activity-dependent
synaptic plasticity that exists at most synapses in the nervous system. In the central nervous …

Striatal fast-spiking interneurons selectively modulate circuit output and are required for habitual behavior

JK O'Hare, H Li, N Kim, E Gaidis, K Ade, J Beck, H Yin… - Elife, 2017 - elifesciences.org
Habit formation is a behavioral adaptation that automates routine actions. Habitual behavior
correlates with broad reconfigurations of dorsolateral striatal (DLS) circuit properties that …

Somatostatin-positive interneurons in the dentate gyrus of mice provide local-and long-range septal synaptic inhibition

M Yuan, T Meyer, C Benkowitz, S Savanthrapadian… - Elife, 2017 - elifesciences.org
Somatostatin-expressing-interneurons (SOMIs) in the dentate gyrus (DG) control formation
of granule cell (GC) assemblies during memory acquisition. Hilar-perforant-path-associated …

Challenging the point neuron dogma: FS basket cells as 2-stage nonlinear integrators

A Tzilivaki, G Kastellakis, P Poirazi - Nature communications, 2019 - nature.com
Interneurons are critical for the proper functioning of neural circuits. While often
morphologically complex, their dendrites have been ignored for decades, treating them as …