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[PDF][PDF] Long-term effects of pediatric acute lymphoblastic leukemia chemotherapy: can recent findings inform old strategies?
ZN Al-Mahayri, MM AlAhmad, BR Ali - Frontiers in Oncology, 2021 - frontiersin.org
During the last few decades, pediatric acute lymphoblastic leukemia (ALL) cure rates have
improved significantly with rates exceeding 90%. Parallel to this remarkable improvement …
improved significantly with rates exceeding 90%. Parallel to this remarkable improvement …
Late-onset cognitive impairment and modifiable risk factors in adult childhood cancer survivors
NS Phillips, KL Stratton, ALM Williams… - JAMA Network …, 2023 - jamanetwork.com
Importance Long-term survivors of childhood cancer may be at elevated risk for new
neurocognitive impairment and decline as they age into adulthood. Objective To determine …
neurocognitive impairment and decline as they age into adulthood. Objective To determine …
Processing efficiency in pediatric cancer survivors: A review and operationalization for outcomes research and clinical utility
JA Trapani, DL Murdaugh - Brain and behavior, 2022 - Wiley Online Library
Objective Childhood cancer and cancer‐related treatments disrupt brain development and
maturation, placing survivors at risk for cognitive late effects. Given that assessment tools …
maturation, placing survivors at risk for cognitive late effects. Given that assessment tools …
Neurocognitive and behavioral outcomes of Chinese survivors of childhood lymphoblastic leukemia
Background Increasing attention has been dedicated to investigate modifiable risk factors of
late effects in survivors of childhood cancer. This study aims to evaluate neurocognitive and …
late effects in survivors of childhood cancer. This study aims to evaluate neurocognitive and …
Risk factors for neurocognitive impairment, emotional distress, and poor quality of life in survivors of pediatric rhabdomyosarcoma: A report from the Childhood Cancer …
E van der Plas, H Darji, DK Srivastava, M Schapiro… - Cancer, 2024 - Wiley Online Library
Background Prevalence and risk of poor psychological outcomes following
rhabdomyosarcoma (RMS) are not well‐established. Methods Participants in this cross …
rhabdomyosarcoma (RMS) are not well‐established. Methods Participants in this cross …
Early life cancer and chemotherapy lead to cognitive deficits related to alterations in microglial-associated gene expression in prefrontal cortex
CJ Laaker, C Cantelon, AB Davis, KR Lloyd… - Brain, behavior, and …, 2023 - Elsevier
Children that survive leukemia are at an increased risk for cognitive difficulties. A better
understanding of the neurobiological changes in response to early life chemotherapy will …
understanding of the neurobiological changes in response to early life chemotherapy will …
The impact of intensified CNS-directed therapy on neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia treated without cranial irradiation
PURPOSE Findings from St Jude Total Therapy Study 16 (Total 16) showed early
intensification of triple intrathecal therapy (ITT) improved CNS disease control for children …
intensification of triple intrathecal therapy (ITT) improved CNS disease control for children …
Neurocognitive outcome and associated factors in long-term, adult survivors of childhood acute lymphoblastic leukemia, treated without cranial radiation therapy
KS Egset, J Stubberud, E Ruud, MA Hjort… - Journal of the …, 2024 - cambridge.org
Objective: There is limited research on neurocognitive outcome and associated risk factors
in long-term, adult survivors of childhood acute lymphoblastic leukemia (ALL), without …
in long-term, adult survivors of childhood acute lymphoblastic leukemia (ALL), without …
Impaired neurocognitive functioning 3 months following diagnosis of high‐risk acute lymphoblastic leukemia: A report from the Children's Oncology Group
KK Hardy, JA Kairalla, AR Gioia… - Pediatric blood & …, 2023 - Wiley Online Library
Purpose Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer
diagnosis. Cognitive late effects develop in 20%–40% of ALL survivors, but the course of …
diagnosis. Cognitive late effects develop in 20%–40% of ALL survivors, but the course of …
The association of environmental factors with neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia (ALL)
SE Nigro, LP Hall, J Harman, VW Willard… - Supportive Care in …, 2024 - Springer
Purpose To investigate the association of environmental factors, rehabilitation services
during therapy and socioeconomic status (SES–insurance type), with neurocognitive …
during therapy and socioeconomic status (SES–insurance type), with neurocognitive …