Functionalizing DNA origami to investigate and interact with biological systems

GA Knappe, EC Wamhoff, M Bathe - Nature Reviews Materials, 2023 - nature.com
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

DNA origami

S Dey, C Fan, KV Gothelf, J Li, C Lin, L Liu… - Nature Reviews …, 2021 - nature.com
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

High-throughput DNA synthesis for data storage

M Yu, X Tang, Z Li, W Wang, S Wang, M Li… - Chemical Society …, 2024 - pubs.rsc.org
With the explosion of digital world, the dramatically increasing data volume is expected to
reach 175 ZB (1 ZB= 1012 GB) in 2025. Storing such huge global data would consume tons …

Probe-based bacterial single-cell RNA sequencing predicts toxin regulation

R McNulty, D Sritharan, SH Pahng, JP Meisch… - Nature …, 2023 - nature.com
Clonal bacterial populations rely on transcriptional variation across individual cells to
produce specialized states that increase fitness. Understanding all cell states requires …

DNA origami: scaffolds for creating higher order structures

F Hong, F Zhang, Y Liu, H Yan - Chemical reviews, 2017 - ACS Publications
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

Building machines with DNA molecules

H Ramezani, H Dietz - Nature Reviews Genetics, 2020 - nature.com
In nature, DNA molecules carry the hereditary information. But DNA has physical and
chemical properties that make it attractive for uses beyond heredity. In this Review, we …

Programmable self-assembly of three-dimensional nanostructures from 10,000 unique components

LL Ong, N Hanikel, OK Yaghi, C Grun, MT Strauss… - Nature, 2017 - nature.com
Nucleic acids (DNA and RNA) are widely used to construct nanometre-scale structures with
ever increasing complexity,,,,,,,,,,,,,, with possible application in fields such as structural …

Rationally engineered nucleic acid architectures for biosensing applications

M **ao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

A characterization of the DNA data storage channel

R Heckel, G Mikutis, RN Grass - Scientific reports, 2019 - nature.com
Owing to its longevity and enormous information density, DNA, the molecule encoding
biological information, has emerged as a promising archival storage medium. However, due …

Engineering nucleic acid structures for programmable molecular circuitry and intracellular biocomputation

J Li, AA Green, H Yan, C Fan - Nature chemistry, 2017 - nature.com
Nucleic acids have attracted widespread attention due to the simplicity with which they can
be designed to form discrete structures and programmed to perform specific functions at the …