Polyphenols, also known as phenolic compounds, are chemical substances containing
aromatic rings as well as at least two hydroxyl groups. Natural phenolic compounds exist …

Food allergy affects more than 500 million people in the world, and its prevalence is
increasing at an alarming rate causing serious public health concerns; however, prevention …

Gut health is important for nutrition absorption, reproduction, and lactation in perinatal and
early weaned mammals. Although melatonin functions in maintaining circadian rhythms and …

Cadmium (Cd) is a widespread environmental contaminant with high toxicity to human
health. Melatonin has been shown to improve Cd‐induced liver damage. However, its …

The evolutionarily ancient methoxyindoleamine, melatonin, has long perplexed investigators
by its versatility of functions and mechanisms of action, which include the regulation of …

Introduction Mast cells are found in all tissues and express numerous surface receptors
allowing them to sense and respond to allergic, autoimmune, environmental …

Influenza A virus (IAV) H1N1 infection is a constant threat to human health and it remains so
due to the lack of an effective treatment. Since melatonin is a potent antioxidant and anti …

Iron overload as a highly risk factor, can be found in almost all human chronic and common
diseases. Iron chelators are often used to treat iron overload; however, patient adherence to …

Disturbed circadian rhythms have been a risk factor for type 2 diabetes mellitus (T2DM).
Melatonin is the major chronobiotic hormone regulating both circadian rhythm and glucose …

Melatonin is a well-known natural hormone, which shows a potential anticancer effect in
many human cancers. Bladder cancer (BLCA) is one of the most malignant human cancers …