The natural product curcumin as an antibacterial agent: Current achievements and problems

C Dai, J Lin, H Li, Z Shen, Y Wang, T Velkov, J Shen - Antioxidants, 2022 - mdpi.com
The rapid spread of antibiotic resistance and lack of effective drugs for treating infections
caused by multi-drug resistant bacteria in animal and human medicine have forced us to find …

Antibacterial mechanism of curcumin: a review

D Zheng, C Huang, H Huang, Y Zhao… - Chemistry & …, 2020 - Wiley Online Library
Curcumin is a plant‐derived polyphenolic active substance with broad‐spectrum
antibacterial properties. Curcumin blocks bacterial growth owing to its structural …

A review of curcumin and its derivatives as anticancer agents

MA Tomeh, R Hadianamrei, X Zhao - International journal of molecular …, 2019 - mdpi.com
Cancer is the second leading cause of death in the world and one of the major public health
problems. Despite the great advances in cancer therapy, the incidence and mortality rates of …

Bactericidal activity of curcumin I is associated with damaging of bacterial membrane

P Tyagi, M Singh, H Kumari, A Kumari… - PloS one, 2015 - journals.plos.org
Curcumin, an important constituent of turmeric, is known for various biological activities,
primarily due to its antioxidant mechanism. The present study focused on the antibacterial …

A comprehensive overview of exosomes as drug delivery vehicles—endogenous nanocarriers for targeted cancer therapy

KB Johnsen, JM Gudbergsson, MN Skov… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Exosomes denote a class of secreted nanoparticles defined by size, surface protein and
lipid composition, and the ability to carry RNA and proteins. They are important mediators of …

[HTML][HTML] An overview on dietary polyphenols and their biopharmaceutical classification system (BCS)

F Truzzi, C Tibaldi, Y Zhang, G Dinelli… - International journal of …, 2021 - mdpi.com
Polyphenols are natural organic compounds produced by plants, acting as antioxidants by
reacting with ROS. These compounds are widely consumed in daily diet and many studies …

[HTML][HTML] The stability, sustained release and cellular antioxidant activity of curcumin nanoliposomes

X Chen, LQ Zou, J Niu, W Liu, SF Peng, CM Liu - Molecules, 2015 - mdpi.com
Curcumin is a multifunctional and natural agent considered to be pharmacologically safe.
However, its application in the food and medical industry is greatly limited by its poor water …

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - Elsevier
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

Curcumin downregulates human tumor necrosis factor-α levels: A systematic review and meta-analysis ofrandomized controlled trials

A Sahebkar, AFG Cicero, LE Simental-Mendía… - Pharmacological …, 2016 - Elsevier
Background Tumor necrosis factor-α (TNF-α) is a key inflammatory mediator and its
reduction is a therapeutic target in several inflammatory diseases. Curcumin, a bioactive …

Curcumin use in pulmonary diseases: State of the art and future perspectives

D Lelli, A Sahebkar, TP Johnston, C Pedone - Pharmacological research, 2017 - Elsevier
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma
longa). It has been used for centuries in Ayurveda (Indian traditional medicine) for the …