[HTML][HTML] Regulation of the host immune system by helminth parasites

RM Maizels, HJ McSorley - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …

Peptide-based synthetic vaccines

M Skwarczynski, I Toth - Chemical science, 2016 - pubs.rsc.org
Classically all vaccines were produced using live or attenuated microorganisms or parts of
them. However, the use of whole organisms, their components or the biological process for …

Hookworm infection

A Loukas, PJ Hotez, D Diemert… - Nature reviews Disease …, 2016 - nature.com
Hookworms are soil-transmitted nematode parasites that can reside for many years in the
small intestine of their human hosts; Necator americanus is the predominant infecting …

Schistosomiasis—from immunopathology to vaccines

DP McManus, R Bergquist, P Cai… - Seminars in …, 2020 - Springer
Schistosomiasis (bilharzia) is a neglected tropical disease caused by trematode worms of
the genus Schistosoma. The transmission cycle involves human (or other mammalian) water …

The yin and yang of human soil-transmitted helminth infections

A Loukas, RM Maizels, PJ Hotez - International journal for parasitology, 2021 - Elsevier
The major soil-transmitted helminths that infect humans are the roundworms, whipworms
and hookworms. Soil-transmitted helminth infections rank among the most important …

Immunomodulation by helminth parasites: defining mechanisms and mediators

HJ McSorley, JP Hewitson, RM Maizels - International journal for …, 2013 - Elsevier
Epidemiological and interventional human studies, as well as experiments in animal
models, strongly indicate that helminth parasitic infections can confer protection from …

Control of helminth ruminant infections by 2030

J Vercruysse, J Charlier, J Van Dijk, ER Morgan… - Parasitology, 2018 - cambridge.org
Helminth infections have large negative impacts on production efficiency in ruminant farming
systems worldwide, and their effective management is essential if livestock production is to …

Schistosomiasis vaccine development: update on human clinical trials

AJ Molehin - Journal of biomedical science, 2020 - Springer
Schistosomiasis causes significant levels of morbidity and mortality in many geographical
regions of the world. The disease is caused by infections with parasitic blood flukes known …

Helminth allergens, parasite-specific IgE, and its protective role in human immunity

CM Fitzsimmons, FH Falcone, DW Dunne - Frontiers in immunology, 2014 - frontiersin.org
The Th2 immune response, culminating in eosinophilia and IgE production, is not only
characteristic of allergy but also of infection by parasitic worms (helminths). Anti-parasite IgE …

[HTML][HTML] Particularities of allergy in the Tropics

L Caraballo, J Zakzuk, BW Lee, N Acevedo… - World Allergy …, 2016 - Elsevier
Allergic diseases are distributed worldwide and their risk factors and triggers vary according
to geographical and socioeconomic conditions. Allergies are frequent in the Tropics but …