Abstract Proteolysis‐targeting chimeras (PROTACs), an emerging paradigm‐shifting
technology, hijacks the ubiquitin‐proteasome system for targeted protein degradation …

Proteolysis targeting chimaeras (PROTACs) is a cutting edge and rapidly growing technique
for new drug discovery and development. Currently, the largest challenge in the molecular …

Throughout time, plants have often displayed medicinal properties that have been
underscored. We often derive medicines involved in treating cancer from components in …

Abstract Aims: Prostate cancer (PCa) is one of the most commonly diagnosed cancers
worldwide. Currently available therapies for metastatic PCa are only marginally effective …

Cancer is a major cause of death worldwide with an increasing incidence rate and is
considered a major public health problem. Distance metastasis to other tissues, high toxicity …

Nimbolide is a tetranortriterpenoid derived from the leaves and flowers of Azadirachta indica
(Neem). It exhibits anticancer activity against a variety of cancers by modulating various …

Abstract Background Prostate cancer (PCa) is the most prominent malignancy among men
worldwide. PCa cells have a high tendency to metastasize to various distant organs, and this …

Purpose Statins extended their hypocholestremic effect to show a promising anticancer
activity. Hepatocellular carcinoma (HCC), the third common cause of cancer-related death …

Exploring the therapeutic potential of Neem (Azadirachta Indica) for the treatment of prostate
cancer: a literature review - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Introduction Nimbolide (Nim), a limonoid obtained from the neem tree, Azadirachta indica,
has several pharmacological properties, including anticancer effects in different type of …