Current status and future prospects of marine natural products (MNPs) as antimicrobials

A Choudhary, LM Naughton, I Montánchez… - Marine drugs, 2017 - mdpi.com
The marine environment is a rich source of chemically diverse, biologically active natural
products, and serves as an invaluable resource in the ongoing search for novel …

Targeting antimicrobial drug resistance with marine natural products

F Barbosa, E Pinto, A Kijjoa, M Pinto… - International journal of …, 2020 - Elsevier
The rise and spread of antimicrobial resistance represents one of the most pressing health
issues of today. Antimicrobial resistance in micro-organisms can arise due to a multiplicity of …

In silico evaluation of antifungal compounds from marine sponges against COVID-19-associated mucormycosis

O Pokharkar, H Lakshmanan, G Zyryanov, M Tsurkan - Marine Drugs, 2022 - mdpi.com
The world is already facing the devastating effects of the SARS-CoV-2 pandemic. A
disseminated mucormycosis epidemic emerged to worsen this situation, causing havoc …

[HTML][HTML] Marine sponge aquaculture towards drug development: An ongoing history of technical, ecological, chemical considerations and challenges

M Maslin, N Gaertner-Mazouni, C Debitus, N Joy… - Aquaculture …, 2021 - Elsevier
Marine sponges have a long history of farming, starting with bath sponges over 5000 years
ago in the Mediterranean. Many species have since been found appropriate for distinct …

Advances in natural products from the marine-sponge-associated microorganisms with antimicrobial activity in the last decade

J Liang, J She, J Fu, J Wang, Y Ye, B Yang, Y Liu… - Marine Drugs, 2023 - mdpi.com
Microorganisms are the dominating source of food and nutrition for sponges and play an
important role in sponge structure, chemical defense, excretion and evolution. In recent …

Harnessing the properties of natural products

A Boufridi, RJ Quinn - Annual review of pharmacology and …, 2018 - annualreviews.org
Natural products (NPs) have been used as traditional medicines since antiquity. With more
than 1060 estimated compounds with molecular weights less than 500 Da representing …

A comprehensive review of marine sponge metabolites, with emphasis on Neopetrosia sp.

N Barzkar, S Sukhikh, O Babich - International Journal of Biological …, 2024 - Elsevier
The secondary metabolites that marine sponges create are essential to the advancement of
contemporary medicine and are often employed in clinical settings. Over the past five years …

Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery

ER Abdelaleem, MN Samy, SY Desoukey, M Liu… - RSC …, 2020 - pubs.rsc.org
Marine organisms have been considered an interesting target for the discovery of different
classes of secondary natural products with wide-ranging biological activities. Sponges …

Metagenomics approaches in discovery and development of new bioactive compounds from marine actinomycetes

GP Mahapatra, S Raman, S Nayak, S Gouda, G Das… - Current …, 2020 - Springer
Marine actinomycetes are prolific sources of marine drug discovery system contributing for
several bioactive compounds of biomedical prominence. Metagenomics, a culture …

Manoalide preferentially provides antiproliferation of oral cancer cells by oxidative stress-mediated apoptosis and DNA damage

HR Wang, JY Tang, YY Wang, AA Farooqi, CY Yen… - Cancers, 2019 - mdpi.com
Marine sponge-derived manoalide has a potent anti-inflammatory effect, but its potential
application as an anti-cancer drug has not yet been extensively investigated. The purpose of …