The Intricate Balance between Life and Death: ROS, cathepsins, and their interplay in cell death and autophagy
Cellular survival hinges on a delicate balance between accumulating damages and repair
mechanisms. In this intricate equilibrium, oxidants, currently considered physiological …
mechanisms. In this intricate equilibrium, oxidants, currently considered physiological …
The selenoprotein methionine sulfoxide reductase B1 (MSRB1)
Methionine (Met) can be oxidized to methionine sulfoxide (MetO), which exist as R-and S-
diastereomers. Present in all three domains of life, methionine sulfoxide reductases (MSR) …
diastereomers. Present in all three domains of life, methionine sulfoxide reductases (MSR) …
MsrB1-regulated GAPDH oxidation plays programmatic roles in sha** metabolic and inflammatory signatures during macrophage activation
HJ Yoo, DW Choi, YJ Roh, YM Lee, JH Lim, S Eo… - Cell Reports, 2022 - cell.com
Classically activated pro-inflammatory macrophages are generated from naive
macrophages by pro-inflammatory cues that dynamically reprogram their fuel metabolism …
macrophages by pro-inflammatory cues that dynamically reprogram their fuel metabolism …
A guide to genetically-encoded redox biosensors: State of the art and opportunities
Genetically-encoded redox biosensors have become invaluable tools for monitoring cellular
redox processes with high spatiotemporal resolution, coupling the presence of the redox …
redox processes with high spatiotemporal resolution, coupling the presence of the redox …
Modern optical approaches in redox biology: Genetically encoded sensors and Raman spectroscopy
AI Kostyuk, DD Rapota, KI Morozova… - Free Radical Biology …, 2024 - Elsevier
The objective of the current review is to summarize the current state of optical methods in
redox biology. It consists of two parts, the first is dedicated to genetically encoded …
redox biology. It consists of two parts, the first is dedicated to genetically encoded …
Low-density Pt nanoarray-based hydrogen peroxide sensing platform and its application in trace sarcosine detection
X Zhang, W **ao, S **e, G Fan, X Shi, H Meng… - Electrochimica Acta, 2023 - Elsevier
Abstract Hydrogen peroxide (H 2 O 2) is an important signaling molecule that regulates
many biological processes. It is of great value to realize rapid, accurate, highly sensitive and …
many biological processes. It is of great value to realize rapid, accurate, highly sensitive and …
Multiple roles of ROS in flowering plant reproduction
Reactive oxygen species (ROS), which are generated by different cellular compartments
through aerobic metabolic pathways, are generally considered to play dual roles in plants …
through aerobic metabolic pathways, are generally considered to play dual roles in plants …
[HTML][HTML] A GFP-based ratiometric sensor for cellular methionine oxidation
Methionine oxidation is a reversible post-translational protein modification, affecting protein
function, and implicated in aging and degenerative diseases. The detection of accumulating …
function, and implicated in aging and degenerative diseases. The detection of accumulating …
Biosensor-linked immunosorbent assay for the quantification of methionine oxidation in target proteins
HM Lee, DW Choi, S Kim, A Lee, M Kim, YJ Roh… - ACS …, 2021 - ACS Publications
Methionine oxidation is involved in regulating the protein activity and often leads to protein
malfunction. However, tools for quantitative analyses of protein-specific methionine …
malfunction. However, tools for quantitative analyses of protein-specific methionine …
[HTML][HTML] Development and Optimization of a Redox Enzyme-Based Fluorescence Biosensor for the Identification of MsrB1 Inhibitors
MsrB1 is a thiol-dependent enzyme that reduces protein methionine-R-sulfoxide and
regulates inflammatory response in macrophages. Therefore, MsrB1 could be a promising …
regulates inflammatory response in macrophages. Therefore, MsrB1 could be a promising …