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Abdominal aortic aneurysm: update on pathogenesis and medical treatments
J Golledge - Nature Reviews Cardiology, 2019 - nature.com
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …
[HTML][HTML] Matrix metalloproteinase in abdominal aortic aneurysm and aortic dissection
EM Maguire, SWA Pearce, R ** review of the literature
H Khan, M Abu-Raisi, M Feasson, F Shaikh… - Biomolecules, 2024 - mdpi.com
Abdominal aortic aneurysm (AAA) is a progressive dilatation of the aorta that can lead to
aortic rupture. The pathophysiology of the disease is not well characterized but is known to …
aortic rupture. The pathophysiology of the disease is not well characterized but is known to …
Mouse models for abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) rupture is estimated to cause 200,000 deaths each year.
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …
Ruptured abdominal aortic aneurysm—epidemiology, predisposing factors, and biology
T Schmitz-Rixen, M Keese, M Hakimi, A Peters… - … archives of surgery, 2016 - Springer
Purpose Abdominal aortic aneurysm is a common degenerative vascular disorder
associated with sudden death due to aortic rupture. This review describes epidemiology …
associated with sudden death due to aortic rupture. This review describes epidemiology …
[HTML][HTML] Dysregulations of key regulators of angiogenesis and inflammation in abdominal aortic aneurysm
D Zalewski, P Chmiel, P Kołodziej, G Borowski… - International Journal of …, 2023 - mdpi.com
Abdominal aortic aneurysm (AAA) is a chronic vascular disease caused by localized
weakening and broadening of the abdominal aorta. AAA is a clearly underdiagnosed …
weakening and broadening of the abdominal aorta. AAA is a clearly underdiagnosed …
TGFβ (transforming growth factor-β) blockade induces a human-like disease in a nondissecting mouse model of abdominal aortic aneurysm
Objective—Current experimental models of abdominal aortic aneurysm (AAA) do not
accurately reproduce the major features of human AAA. We hypothesized that blockade of …
accurately reproduce the major features of human AAA. We hypothesized that blockade of …