[HTML][HTML] Astroglia support, regulate and reinforce brain barriers

A Verkhratsky, A Pivoriūnas - Neurobiology of Disease, 2023 - Elsevier
Nervous system is segregated from the body by the complex system of barriers. The CNS is
protected by (i) the blood–brain and blood-spinal cord barrier between the intracerebral and …

The role of motile cilia in the development and physiology of the nervous system

C Ringers, EW Olstad… - … Transactions of the …, 2020 - royalsocietypublishing.org
Motile cilia are miniature, whip-like organelles whose beating generates a directional fluid
flow. The flow generated by ciliated epithelia is a subject of great interest, as defective ciliary …

[HTML][HTML] A brainstem–hypothalamus neuronal circuit reduces feeding upon heat exposure

M Benevento, A Alpár, A Gundacker, L Afjehi… - Nature, 2024 - nature.com
Empirical evidence suggests that heat exposure reduces food intake. However, the
neurocircuit architecture and the signalling mechanisms that form an associative interface …

Neuronal diversity of neuropeptide signaling, including galanin, in the mouse locus coeruleus

M Caramia, RA Romanov, S Sideromenos… - Proceedings of the …, 2023 - pnas.org
The locus coeruleus (LC) is a small nucleus in the pons from which ascending and
descending projections innervate major parts of the central nervous system. Its major …

A hypothalamic dopamine locus for psychostimulant-induced hyperlocomotion in mice

S Korchynska, P Rebernik, M Pende, L Boi… - Nature …, 2022 - nature.com
The lateral septum (LS) has been implicated in the regulation of locomotion. Nevertheless,
the neurons synchronizing LS activity with the brain's clock in the suprachiasmatic nucleus …

The periaxonal space as a conduit for cerebrospinal fluid flow to peripheral organs

X Li, S Wang, D Zhang, Y Feng, Y Liu, W Yu… - Proceedings of the …, 2024 - pnas.org
Mechanisms controlling the movement of the cerebrospinal fluid (CSF) toward peripheral
nerves are poorly characterized. We found that, in addition to the foramina Magendie and …

[HTML][HTML] Intercellular communication in the central nervous system as deduced by chemical neuroanatomy and quantitative analysis of images: Impact on …

D Guidolin, C Tortorella, M Marcoli, G Maura… - International journal of …, 2022 - mdpi.com
In the last decades, new evidence on brain structure and function has been acquired by
morphological investigations based on synergic interactions between biochemical anatomy …

Unveiling hypothalamic molecular signatures via retrograde viral tracing and single-cell transcriptomics

M Junaid, HK Choe, K Kondoh, EJ Lee, SB Lim - Scientific Data, 2023 - nature.com
Despite the importance of hypothalamic neurocircuits in regulating homeostatic and survival-
related behaviors, our understanding of the intrinsic molecular identities of neural …

[HTML][HTML] Variant-to-gene-map** analyses reveal a role for the hypothalamus in genetic susceptibility to inflammatory bowel disease

C Lasconi, MC Pahl, DL Cousminer, CA Doege… - Cellular and Molecular …, 2021 - Elsevier
Background & Aims Inflammatory bowel disease (IBD) is a polygenic disorder characterized
principally by dysregulated inflammation impacting the gastrointestinal tract. However, there …

[HTML][HTML] Chondroitin sulfate proteoglycan-5 forms perisynaptic matrix assemblies in the adult rat cortex

A Pintér, Z Hevesi, P Zahola, A Alpár, J Hanics - Cellular Signalling, 2020 - Elsevier
Composition of the brain extracellular matrix changes in time as maturation proceeds.
Chondroitin sulfate proteoglycan 5 (CSPG-5), also known as neuroglycan C, has been …