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Eyeing up the future of the pupillary light reflex in neurodiagnostics
CA Hall, RP Chilcott - Diagnostics, 2018 - mdpi.com
The pupillary light reflex (PLR) describes the constriction and subsequent dilation of the
pupil in response to light as a result of the antagonistic actions of the iris sphincter and …
pupil in response to light as a result of the antagonistic actions of the iris sphincter and …
Innovative diagnostic tools for early detection of Alzheimer's disease
Current state-of-the-art diagnostic measures of Alzheimer's disease (AD) are invasive
(cerebrospinal fluid analysis), expensive (neuroimaging) and time-consuming …
(cerebrospinal fluid analysis), expensive (neuroimaging) and time-consuming …
Retinal changes in Alzheimer's disease—integrated prospects of imaging, functional and molecular advances
Alzheimer's Disease (AD) is a devastating neurodegenerative disorder of the brain, clinically
characterised by cognitive deficits that gradually worsen over time. There is, at present, no …
characterised by cognitive deficits that gradually worsen over time. There is, at present, no …
The eye as a biomarker for Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder resulting in dementia
and eventual death. It is the leading cause of dementia and the number of cases are …
and eventual death. It is the leading cause of dementia and the number of cases are …
Light-induced pupillary responses in Alzheimer's disease
The impact of Alzheimer's disease (AD) on the pupillary light response (PLR) is
controversial, being dependent on the stage of the disease and on the experimental …
controversial, being dependent on the stage of the disease and on the experimental …
Untreated poor vision: a contributing factor to late-life dementia
Ophthalmologic abnormalities have been described in patients with dementia, but the extent
to which poor vision and treatment for visual disorders affect cognitive decline is not well …
to which poor vision and treatment for visual disorders affect cognitive decline is not well …
Alzheimer's disease and retinal neurodegeneration
L Guo, J Duggan, MF Cordeiro - Current Alzheimer Research, 2010 - ingentaconnect.com
Alzheimer's disease (AD) is the major cause of dementia in the world. Although the
entorhinal cortex and hippocampal complex are best known as the sites of early pathology …
entorhinal cortex and hippocampal complex are best known as the sites of early pathology …
Cholinergic deficiency in Alzheimer's and Parkinson's disease: evaluation with pupillometry
DF Fotiou, V Stergiou, D Tsiptsios, C Lithari… - International Journal of …, 2009 - Elsevier
The aim of the study was to evaluate the cholinergic deficiency in Alzheimer's (AD) and
Parkinson's disease (PD). For this purpose, pupil size changes and mobility were assessed …
Parkinson's disease (PD). For this purpose, pupil size changes and mobility were assessed …
Retinal pathology as biomarker for cognitive impairment and Alzheimer's disease
Alzheimer's disease (AD) is the most common cause of dementia. Furthermore, over the last
few decades, there has been a shift towards identifying earlier stages of AD, which include …
few decades, there has been a shift towards identifying earlier stages of AD, which include …
Eye tracking–The overlooked method to measure cognition in neurodegeneration?
Eye tracking (ET) studies are becoming increasingly popular due to rapid methodological
and technological advances as well as the development of cost efficient and portable eye …
and technological advances as well as the development of cost efficient and portable eye …