New blood vessels formation from the existing vasculature is called angiogenesis. It is an
essential physiological process for the growth of cells, tissue repair, wound healing, and …

Five vascular endothelial growth factor receptor (VEGFR) ligands (VEGF-A,-B,–C,-D, and
placental growth factor [PlGF]) constitute the VEGF family. VEGF-A binds VEGF receptors 1 …

Several lines of evidence suggest that stress induces the neurovascular dysfunction
associated with increased blood–brain barrier (BBB) permeability, which could be an …

The blood–brain barrier (BBB) is formed by tightly connected cerebrovascular endothelial
cells, but its normal function also depends on paracrine interactions between the brain …

Vascular endothelial growth-factor receptors (VEGFRs) regulate the cardiovascular system.
VEGFR1 is required for the recruitment of haematopoietic precursors and migration of …

Abstract One Von Hippel-Lindau (VHL) tumor suppressor gene is lost in most renal cell
carcinomas while the nondeleted allele exhibits hypermethylation-induced inactivation or …

The VEGF (vascular endothelial growth factor) family and its receptors are essential
regulators of angiogenesis and vascular permeability. Currently, the VEGF family consists of …

The VEGF/VPF (vascular endothelial growth factor/vascular permeability factor) ligands and
receptors are crucial regulators of vasculogenesis, angiogenesis, lymphangiogenesis and …

Preeclampsia, a systemic syndrome of pregnancy clinically characterized by new onset of
proteinuria and hypertension, is associated with significant morbidity and mortality to both …

Purpose Renal cell carcinoma (RCC) is characterized by loss of von Hippel Lindau tumor
suppressor gene activity, resulting in high expression of pro-angiogenic growth factors …