Ventilator-associated pneumonia in adults: a narrative review
Ventilator-associated pneumonia (VAP) is one of the most frequent ICU-acquired infections.
Reported incidences vary widely from 5 to 40% depending on the setting and diagnostic …
Reported incidences vary widely from 5 to 40% depending on the setting and diagnostic …
Rescuing the last-line polymyxins: achievements and challenges
Antibiotic resistance is a major global health challenge and, worryingly, several key Gram
negative pathogens can become resistant to most currently available antibiotics. Polymyxins …
negative pathogens can become resistant to most currently available antibiotics. Polymyxins …
International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the …
The most recent European guidelines and task force reports on hospital-acquired
pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost 10 …
pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost 10 …
Aminoglycosides: an overview
KM Krause, AW Serio, TR Kane… - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
Aminoglycosides are natural or semisynthetic antibiotics derived from actinomycetes. They
were among the first antibiotics to be introduced for routine clinical use and several …
were among the first antibiotics to be introduced for routine clinical use and several …
Trends in human fecal carriage of extended-spectrum β-lactamases in the community: toward the globalization of CTX-M
PL Woerther, C Burdet, E Chachaty… - Clinical microbiology …, 2013 - Am Soc Microbiol
In the last 10 years, extended-spectrum β-lactamase-producing enterobacteria (ESBL-E)
have become one of the main challenges for antibiotic treatment of enterobacterial …
have become one of the main challenges for antibiotic treatment of enterobacterial …
Bacterial and fungal infections in acute-on-chronic liver failure: prevalence, characteristics and impact on prognosis
Bacterial infection is a frequent trigger of acute-on-chronic liver failure (ACLF), syndrome
that could also increase the risk of infection. This investigation evaluated prevalence and …
that could also increase the risk of infection. This investigation evaluated prevalence and …
Strategies to prevent ventilator-associated pneumonia in acute care hospitals: 2014 update
Previously published guidelines are available that provide comprehensive
recommendations for detecting and preventing healthcare-associated infections (HAIs). The …
recommendations for detecting and preventing healthcare-associated infections (HAIs). The …
Mechanisms of antimicrobial resistance in Gram-negative bacilli
É Ruppé, PL Woerther, F Barbier - Annals of intensive care, 2015 - Springer
The burden of multidrug resistance in Gram-negative bacilli (GNB) now represents a daily
issue for the management of antimicrobial therapy in intensive care unit (ICU) patients. In …
issue for the management of antimicrobial therapy in intensive care unit (ICU) patients. In …
Association between selective decontamination of the digestive tract and in-hospital mortality in intensive care unit patients receiving mechanical ventilation: a …
Importance The effectiveness of selective decontamination of the digestive tract (SDD) in
critically ill adults receiving mechanical ventilation is uncertain. Objective To determine …
critically ill adults receiving mechanical ventilation is uncertain. Objective To determine …
Antibiotic resistance in Enterobacteriaceae: mechanisms and clinical implications
J Iredell, J Brown, K Tagg - Bmj, 2016 - bmj.com
Resistance of the Enterobacteriaceae to antibiotics, especially of the β lactam type, is
increasingly dominated by the mobilization of continuously expressed single genes that …
increasingly dominated by the mobilization of continuously expressed single genes that …