This review describes the development of enantioselective methods for the ring opening of
cyclopropanes. Both approaches based on the reaction of nonchiral cyclopropanes and …

Three-and four-membered rings, widespread motifs in nature and medicinal chemistry, have
fascinated chemists ever since their discovery. However, due to energetic considerations …

In this review, synthetic and mechanistic aspects of key methodologies that exploit C–C
single-bond cleavage of strained ring systems are highlighted. The focus is on transition …

The transition-metal-catalyzed “cut and sew” transformation has recently emerged as a
useful strategy for preparing complex molecular structures. After oxidative addition of a …

The past decade has witnessed the golden age of homogeneous gold-catalyzed reactions,
especially those that involve the transformation of highly strained molecules into complex …

Complex natural products bearing strained cyclobutane subunits, including terpenoids,
alkaloids and steroids, not only display fascinating architectures, but also show potent …

Silacycles have exhibited significant potential for application in the fields of medicinal
chemistry, agrochemistry, and materials science. Accordingly, the development of effective …

This review summarizes synthetic developments reported from 1987 to 2019 that exploit C–
C single bond cleavage of cyclopropylamine-based systems. The synthetic and mechanistic …

Despite impressive advances in the construction of enantioenriched silacarbocycles
featuring silicon‐stereogenic centers via a selection of well‐defined sila‐synthons, the …

Direct synthesis of gem‐difluorinated carbocyclic molecules represents a longstanding
challenge in organic chemistry. Herein, a Rh‐catalyzed [3+ 2] cycloaddition reaction …