Copper toxicity, oxidative stress, and antioxidant nutrients
LM Gaetke, CK Chow - Toxicology, 2003 - Elsevier
Copper (Cu) is an integral part of many important enzymes involved in a number of vital
biological processes. Although normally bound to proteins, Cu may be released and …
biological processes. Although normally bound to proteins, Cu may be released and …
Oxidative stress as a regulator of gene expression in the vasculature
C Kunsch, RM Medford - Circulation research, 1999 - Am Heart Assoc
Oxidative stress and the production of intracellular reactive oxygen species (ROS) have
been implicated in the pathogenesis of a variety of diseases. In excess, ROS and their …
been implicated in the pathogenesis of a variety of diseases. In excess, ROS and their …
Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-κB through an increased production of …
In this study we examined the effect of oxidized low density lipoprotein (ox-LDL) on the
intracellular production of reactive oxygen species (ROS) in bovine aortic endothelial cells …
intracellular production of reactive oxygen species (ROS) in bovine aortic endothelial cells …
Quercetin attenuates atherosclerotic inflammation and adhesion molecule expression by modulating TLR-NF-κB signaling pathway
S Bhaskar, PR Sudhakaran, A Helen - Cellular immunology, 2016 - Elsevier
Adhesion molecules expressed by activated endothelial cells play key role in regulating
leukocyte trafficking to sites of inflammation. The present study attempted to explore whether …
leukocyte trafficking to sites of inflammation. The present study attempted to explore whether …
Upregulation of endothelial receptor for oxidized LDL (LOX-1) by oxidized LDL and implications in apoptosis of human coronary artery endothelial cells: evidence from …
D Li, JL Mehta - Arteriosclerosis, thrombosis, and vascular biology, 2000 - Am Heart Assoc
A specific lectinlike endothelial receptor for oxidized low density lipoprotein (LOX-1), distinct
from the scavenger receptor in monocytes/macrophages, has been identified and cloned. In …
from the scavenger receptor in monocytes/macrophages, has been identified and cloned. In …
Production of the long pentraxin PTX3 in advanced atherosclerotic plaques
MS Rolph, S Zimmer, B Bottazzi… - … , and vascular biology, 2002 - Am Heart Assoc
Elevated plasma levels of the pentraxin protein family member C-reactive protein (CRP) are
associated with increased risk of cardiovascular disease in both healthy and high-risk …
associated with increased risk of cardiovascular disease in both healthy and high-risk …
Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: the potential role of transcription factor NF-κB
D Li, T Saldeen, F Romeo, JL Mehta - Circulation, 2000 - Am Heart Assoc
Background—We demonstrated earlier that angiotensin II (Ang II), by AT1 receptor
activation, upregulates oxidized LDL (ox-LDL) endothelial receptor LOX-1 gene expression …
activation, upregulates oxidized LDL (ox-LDL) endothelial receptor LOX-1 gene expression …
c-Kit modifies the inflammatory status of smooth muscle cells
Background c-Kit is a receptor tyrosine kinase present in multiple cell types, including
vascular smooth muscle cells (SMC). However, little is known about how c-Kit influences …
vascular smooth muscle cells (SMC). However, little is known about how c-Kit influences …
Clinical implications of matrix metalloproteinases
Matrix metalloproteinases (MMPs) are a family of neutral proteinases that are important for
normal development, wound healing, and a wide variety of pathological processes …
normal development, wound healing, and a wide variety of pathological processes …
Lipid oxidation products in cell signaling
G Leonarduzzi, MC Arkan, H Başağa… - Free Radical Biology …, 2000 - Elsevier
The recent research on the impact that oxidative changes of biolipids could have in
pathophysiology serves to explain how free radical–driven reactions not only are considered …
pathophysiology serves to explain how free radical–driven reactions not only are considered …