[HTML][HTML] Spatial transcriptomics: Integrating morphology and molecular mechanisms of kidney diseases
P Isnard, BD Humphreys - The American Journal of Pathology, 2024 - Elsevier
The recent arrival of high-resolution spatial transcriptomics (ST) technologies is generating a
veritable revolution in life sciences, enabling biomolecules to be measured in their native …
veritable revolution in life sciences, enabling biomolecules to be measured in their native …
Single-cell advances in investigating and understanding chronic kidney disease and diabetic kidney disease
Chronic kidney disease (CKD) and its subset diabetic kidney disease are progressive
conditions that affect> 850 million people worldwide. Diabetes, hypertension, and …
conditions that affect> 850 million people worldwide. Diabetes, hypertension, and …
New approaches to acute kidney injury
S Noel, R Kapoor, H Rabb - Clinical Kidney Journal, 2024 - academic.oup.com
Acute kidney injury (AKI) is a common and serious clinical syndrome that involves complex
interplay between different cellular, molecular, metabolic and immunologic mechanisms …
interplay between different cellular, molecular, metabolic and immunologic mechanisms …
[HTML][HTML] A bioprinted and scalable model of human tubulo-interstitial kidney fibrosis
D Bouwens, N Kabgani, C Bergerbit, H Kim, S Ziegler… - Biomaterials, 2025 - Elsevier
Chronic kidney disease (CKD) affects more than 10% of the global population. As kidney
function negatively correlates with the presence of interstitial fibrosis, the development of …
function negatively correlates with the presence of interstitial fibrosis, the development of …
New tools to study renal fibrogenesis
X Liao, E Scheidereit, C Kuppe - Current Opinion in Nephrology …, 2024 - journals.lww.com
As further single-cell and spatial multiomic approaches are being developed, opportunities
to apply these methods to human kidney tissues expand similarly. Careful design and …
to apply these methods to human kidney tissues expand similarly. Careful design and …
[CITAAT][C] Emerging high resolution spatial transcriptomic technologies in kidney research
Q Xuanyuan, H Wu… - Nephrology Dialysis …, 2024 - academic.oup.com
The spatial organization of cells, including their arrangement relative to neighboring cells
and extracellular matrix (ECM) components, plays a crucial role in dictating cell behavior …
and extracellular matrix (ECM) components, plays a crucial role in dictating cell behavior …