Cancer cachexia and its pathophysiology: links with sarcopenia, anorexia and asthenia

S Peixoto da Silva, JMO Santos… - Journal of cachexia …, 2020 - Wiley Online Library
Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of skeletal
muscle mass, along with adipose tissue wasting, systemic inflammation and other metabolic …

TNF-α and cancer cachexia: Molecular insights and clinical implications

HJ Patel, BM Patel - Life sciences, 2017 - Elsevier
Cancer cachexia characterized by a chronic wasting syndrome, involves skeletal muscle
loss and adipose tissue loss and resistance to conventional nutritional support. Cachexia is …

Cancer cachexia, mechanism and treatment

T Aoyagi, KP Terracina, A Raza… - World journal of …, 2015 - pmc.ncbi.nlm.nih.gov
It is estimated that half of all patients with cancer eventually develop a syndrome of
cachexia, with anorexia and a progressive loss of adipose tissue and skeletal muscle mass …

Mechanisms of cancer-related fatigue

JL Ryan, JK Carroll, EP Ryan, KM Mustian… - The …, 2007 - academic.oup.com
Cancer-related fatigue (CRF) is one of the most prevalent symptoms patients with cancer
experience, both during and after treatment. CRF is pervasive and affects patients' quality of …

Cancer cachexia: impact, mechanisms and emerging treatments

VC Vaughan, P Martin, PA Lewandowski - Journal of cachexia, sarcopenia …, 2013 - Springer
Many forms of cancer present with a complex metabolic profile characterised by loss of lean
body mass known as cancer cachexia. The physical impact of cachexia contributes to …

Interleukin-6 and cachexia in ApcMin/+ mice

KA Baltgalvis, FG Berger, MMO Pena… - American journal …, 2008 - journals.physiology.org
The Apc Min/+ mouse has a mutation in the Apc tumor suppressor gene and develops
intestinal polyps, beginning at 4 wk of age. This mouse develops cachexia by 6 mo …

Simultaneous extraction of metabolome and lipidome with methyl tert-butyl ether from a single small tissue sample for ultra-high performance liquid chromatography …

S Chen, M Hoene, J Li, Y Li, X Zhao, HU Häring… - … of chromatography A, 2013 - Elsevier
A common challenge for scientists working with animal tissue or human biopsy samples is
the limitation of material and consequently, the difficulty to perform comprehensive metabolic …

Protein calorie malnutrition, nutritional intervention and personalized cancer care

A Gangadharan, SE Choi, A Hassan, NM Ayoub… - …, 2017 - pmc.ncbi.nlm.nih.gov
Cancer patients often experience weight loss caused by protein calorie malnutrition (PCM)
during the course of the disease or treatment. PCM is expressed as severe if the patient has …

Physical function and all-cause mortality in older adults diagnosed with cancer: a systematic review and meta-analysis

Y Ezzatvar, R Ramírez-Vélez… - The Journals of …, 2021 - academic.oup.com
Background Physical function is an independent predictor of numerous chronic diseases,
but its association with all-cause mortality in older adults diagnosed with cancer has …

[HTML][HTML] New insights on the regulation of cancer cachexia by N-3 polyunsaturated fatty acids

R Gorjao, CMM Dos Santos, TDA Serdan… - Pharmacology & …, 2019 - Elsevier
Cancer cachexia is a multifactorial syndrome that develops during malignant tumor growth.
Changes in plasma levels of several hormones and inflammatory factors result in an intense …