Background Gut microbiota dysbiosis and sarcopenia commonly occur in the elderly.
Although the concept of the gut–muscle axis has been raised, the casual relationship is still …

Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …

A key metabolic activity of the gut microbiota is the fermentation of non-digestible
carbohydrate, which generates short-chain fatty acids (SCFAs) as the principal end …

The gut microbiota represents a 'metabolic organ'that can regulate human metabolism. Intact
gut microbiota contributes to host homeostasis, whereas compositional perturbations …

Evidence suggests that gut microbiota composition and diversity can be a determinant of
skeletal muscle metabolism and functionality. This is true in catabolic (sarcopenia and …

Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of skeletal
muscle mass, along with adipose tissue wasting, systemic inflammation and other metabolic …

Human gut microbiota is able to influence the host physiology by regulating multiple
processes, including nutrient absorption, inflammation, oxidative stress, immune function …

Cancer cachexia is a devastating, multifactorial and often irreversible syndrome that affects
around 50–80% of cancer patients, depending on the tumour type, and that leads to …

Metabolic reprogramming occurs in tumors to foster cancer cell proliferation, survival and
metastasis, but as well at a systemic level affecting the whole organism, eventually leading …

Cachexia is a systemic condition that occurs during many neoplastic diseases, such as
cancer. Cachexia in cancer is characterized by loss of body weight and muscle and by …