When the Host Encounters the Cell Wall and Vice Versa

K Kho, T Cheng, N Buddelmeijer… - Annual Review of …, 2024 - annualreviews.org
Peptidoglycan (PGN) and associated surface structures such as secondary polymers and
capsules have a central role in the physiology of bacteria. The exoskeletal PGN …

Peptidoglycan fragment release and NOD activation by commensal Neisseria species from humans and other animals

TN Harris-Jones, JM Chan, KT Hackett… - Infection and …, 2024 - journals.asm.org
Neisseria gonorrhoeae, a human restricted pathogen, releases inflammatory peptidoglycan
(PG) fragments that contribute to the pathophysiology of pelvic inflammatory disease. The …

Mechanisms of Sensory Signal Transduction Across the Envelope in the CpxRA System of Escherichia coli

THS Cho - 2024 - era.library.ualberta.ca
The bacterial envelope is a critical barrier that not only shields bacteria from harsh
environments but also serves as a key organizing centre for processes such as metabolism …

Mutation of mltG increases peptidoglycan fragment release, cell size, and antibiotic susceptibility in Neisseria gonorrhoeae

TN Harris-Jones, KM Pérez Medina… - Journal of …, 2023 - journals.asm.org
Infection with Neisseria gonorrhoeae leads to inflammation that is responsible for the
disease symptoms of gonococcal urethritis, cervicitis, and pelvic inflammatory disease …

Mutational analysis of LtgC, a lytic transglycosylase required for cell separation in Neisseria gonorrhoeae

RE Schaub, K Perez-Medina, J Tomberg, RA Nicholas… - bioRxiv, 2023 - biorxiv.org
Lytic transglycosylases function to degrade peptidoglycan strands that comprise the
bacterial cell wall. Degradation of peptidoglycan at the septum following cell division is …

[PDF][PDF] Manuscript in preparation for submission

TN Harris-Jones - … on Neisseria-host interactions in an in vivo …, 2023 - asset.library.wisc.edu
Peptidoglycan (PG) is a structural macromolecule that is important for bacterial survival.
Multicellular organisms, such as humans, have evolved ways to detect PG and respond to …