Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

Growth hormone (GH) and insulin-like growth factor 1 (IGF1) are important regulators of
bone remodelling and metabolism and have an essential role in the achievement and …

Objective The aim of the Acromegaly Consensus Group was to revise and update the
consensus on diagnosis and treatment of acromegaly comorbidities last published in 2013 …

Osteoporosis is a skeletal disorder characterized by decreased mass and compromised
bone strength predisposing to an increased risk of fractures. Although idiopathic …

Background Despite COVID-19 being identified as severe respiratory viral infection,
progressively many relevant endocrine manifestations have been reported greatly …

Background Acromegaly is a rare and underdiagnosed disorder caused, in more than 95%
of cases, by a growth hormone (GH)-secreting pituitary adenoma. The GH hypersecretion …

Background. Growth hormone (GH) and insulin‐like growth factor (IGF‐1) are fundamental
in skeletal growth during puberty and bone health throughout life. GH increases tissue …

Abstract More than 2.1 million age-related fractures occur in the United States annually,
resulting in an immense socioeconomic burden. Importantly, the age-related deterioration of …

Besides their growth-promoting properties, GH and IGF-1 regulate a broad spectrum of
biological functions in several organs, including the kidney. This review focuses on the renal …

Introduction Acromegaly is a rare, insidious disease resulting from the overproduction of
growth hormone (GH) and insulin-like growth factor 1 (IGF-1), and is associated with a range …