The objective was to update previous evidence‐based medicine reviews of treatments for
motor symptoms of Parkinson's disease published between 2002 and 2005. Level I …

Gait impairments in Parkinson′ s disease (PD) are exacerbated under dual‐task conditions
requiring the simultaneous performance of cognitive or motor tasks. Dual‐task walking …

The final goal of motor learning, a complex process that includes both implicit and explicit (or
declarative) components, is the optimization and automatization of motor skills. Motor …

Deep brain stimulation in the subthalamic nucleus is an effective and safe surgical
procedure that has been shown to reduce the motor dysfunction of patients with advanced …

Objectives: The globus pallidus internus (GPi) has been the primary target for deep brain
stimulation (DBS) to treat severe medication-refractory dystonia. Some patients with primary …

Over the past 15 years, computational models have had a considerable impact on basal-
ganglia research. Most of these models implement multiple distinct basal-ganglia pathways …

Humans often accept the status quo when faced with conflicting choice alternatives.
However, it is unknown how neural pathways connecting cognition with action modulate this …

Deep brain stimulation (DBS) has recently been proven to be an effective therapy for
medication-refractory symptoms of Parkinson's disease. As the evidence base continues to …

Background Novel deep brain stimulation (DBS) paradigms are being explored in an effort
to further optimize therapeutic outcome for patients with Parkinson's disease (PD). One …

Hedonic overconsumption contributing to obesity involves altered activation within the
mesolimbic dopamine system. Dysregulation of dopamine signaling in the nucleus …