ESKAPE pathogens: antimicrobial resistance, epidemiology, clinical impact and therapeutics

WR Miller, CA Arias - Nature Reviews Microbiology, 2024 - nature.com
The rise of antibiotic resistance and a dwindling antimicrobial pipeline have been
recognized as emerging threats to public health. The ESKAPE pathogens—Enterococcus …

Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review

K Kopotsa, J Osei Sekyere… - Annals of the New York …, 2019 - Wiley Online Library
Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

Global spread and evolutionary convergence of multidrug-resistant and hypervirulent Klebsiella pneumoniae high-risk clones

G Arcari, A Carattoli - Pathogens and Global Health, 2023 - Taylor & Francis
For people living in developed countries life span is growing at a faster pace than ever. One
of the main reasons for such success is attributable to the introduction and extensive use in …

Phenotypic and genotypic detection of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in Accra, Ghana

FP Dwomoh, FCN Kotey, NTKD Dayie, MM Osei… - PLoS …, 2022 - journals.plos.org
Aim To describe the occurrence of carbapenem resistance among multidrug-resistant (MDR)
Escherichia coli and Klebsiella pneumoniae isolated from clinical specimens in Accra using …

Emergence of carbapenemase-producing hypervirulent Klebsiella pneumoniae in Switzerland

O Hallal Ferreira Raro, P Nordmann… - Antimicrobial agents …, 2023 - journals.asm.org
Increasing occurrence of multidrug-resistant (MDR) and hypervirulent (hv) Klebsiella
pneumoniae (MDR-hvKp) convergent clones is being observed. Those strains have the …

[HTML][HTML] Phage delivered CRISPR-Cas system to combat multidrug-resistant pathogens in gut microbiome

A Nath, R Bhattacharjee, A Nandi, A Sinha… - Biomedicine & …, 2022 - Elsevier
The Host-microbiome interactions that exist inside the gut microbiota operate in a synergistic
and abnormal manner. Additionally, the normal homeostasis and functioning of gut …

Klebsiella pneumoniae infections in COVID-19 patients: a 2-month retrospective analysis in an Italian hospital

G Arcari, G Raponi, F Sacco… - International journal …, 2020 - pmc.ncbi.nlm.nih.gov
Italy has experienced one of the harshest and earliest COVID-19 (coronavirus disease
2019) epidemics, with the number of patients infected following, from the end of February up …

The emergence of highly resistant and hypervirulent Klebsiella pneumoniae CC14 clone in a tertiary hospital over 8 years

S Hala, M Malaikah, J Huang, W Bahitham, O Fallatah… - Genome medicine, 2024 - Springer
Background Klebsiella pneumoniae is a major bacterial and opportunistic human pathogen,
increasingly recognized as a healthcare burden globally. The convergence of resistance …

Genomic and resistance epidemiology of Gram-negative bacteria in Africa: a systematic review and phylogenomic analyses from a one health perspective

J Osei Sekyere, MA Reta - Msystems, 2020 - journals.asm.org
Antibiotic resistance (AR) remains a major threat to public and animal health globally.
However, AR ramifications in develo** countries are worsened by limited molecular …

Genomic evolution of the globally disseminated multidrug-resistant Klebsiella pneumoniae clonal group 147

C Rodrigues, S Desai, V Passet… - Microbial …, 2022 - microbiologyresearch.org
The rapid emergence of multidrug-resistant Klebsiella pneumoniae is being driven largely
by the spread of specific clonal groups (CGs). Of these, CG147 includes 7-gene multilocus …