Therapeutic strategies focussed on the pulp preservation, are important when managing
vital teeth with deep caries and an exposed pulp. These vital pulp treatments (VPTs); …

Caries prevalence remains high throughout the world, with the burden of disease
increasingly affecting older and socially disadvantaged groups in Western cultures. If left …

Dental caries is a chronic infectious disease resulting from the penetration of oral bacteria
into the enamel and dentin. Microorganisms subsequently trigger inflammatory responses in …

Biodentine is a calcium‐silicate based material that has drawn attention in recent years and
has been advocated to be used in various clinical applications, such as root perforations …

Laurent P, Camps J, About I. Biodentine™ induces TGF‐β1 release from human pulp cells
and early dental pulp mineralization. International Endodontic Journal, 45, 439–448, 2012 …

Introduction During dentinogenesis, growth factors become entrapped in the dentin matrix
that can later be released by demineralization. Their effect on pulpal stem cell migration …

This practice-based, randomized clinical trial evaluated and compared the success of direct
pulp cap** in permanent teeth with MTA (mineral trioxide aggregate) or CaOH (calcium …

Clinical Relevance Confusion and misconceptions surround direct and indirect pulp
cap**. This review of the literature provides evidence-based recommendations to guide …

Dental tissue infection and disease result in acute and chronic activation of the innate
immune response, which is mediated by molecular and cellular signaling. Different cell …

Stem cells from human exfoliated deciduous teeth (SHED) have been isolated and
characterized as multipotent cells. However, it is not known whether SHED can generate a …