The role of cytochrome P450-mediated detoxification in insect adaptation to xenobiotics

K Lu, Y Song, R Zeng - Current Opinion in Insect Science, 2021‏ - Elsevier
Insect cytochrome P450 monooxygenases (P450s) are well known to be involved in
metabolic detoxification of xenobiotics, such as phytochemicals, insecticides and …

Insecticide resistance in mosquitoes: impact, mechanisms, and research directions

N Liu - Annual review of entomology, 2015‏ - annualreviews.org
Mosquito-borne diseases, the most well known of which is malaria, are among the leading
causes of human deaths worldwide. Vector control is a very important part of the global …

Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?

H Ranson, R N'guessan, J Lines, N Moiroux… - Trends in …, 2011‏ - cell.com
The use of pyrethroid insecticides in malaria vector control has increased dramatically in the
past decade through the scale up of insecticide treated net distribution programmes and …

Insect CYP genes and P450 enzymes

R Feyereisen - Insect molecular biology and biochemistry, 2012‏ - Elsevier
Publisher Summary This chapter discusses the insect CYP genes and P450 enzymes.
Cytochrome P450, or CYP genes, constitutes one of the largest family of genes, with …

[HTML][HTML] Impact of environment on mosquito response to pyrethroid insecticides: facts, evidences and prospects

TE Nkya, I Akhouayri, W Kisinza, JP David - Insect biochemistry and …, 2013‏ - Elsevier
By transmitting major human diseases such as malaria, dengue fever and filariasis,
mosquito species represent a serious threat worldwide in terms of public health, and pose a …

Role of cytochrome P450s in insecticide resistance: impact on the control of mosquito-borne diseases and use of insecticides on Earth

JP David, HM Ismail… - … Transactions of the …, 2013‏ - royalsocietypublishing.org
The fight against diseases spread by mosquitoes and other insects has enormous
environmental, economic and social consequences. Chemical insecticides remain the first …

CYP6 P450 Enzymes and ACE-1 Duplication Produce Extreme and Multiple Insecticide Resistance in the Malaria Mosquito Anopheles gambiae

CV Edi, L Djogbenou, AM Jenkins, K Regna… - PLoS …, 2014‏ - journals.plos.org
Malaria control relies heavily on pyrethroid insecticides, to which susceptibility is declining in
Anopheles mosquitoes. To combat pyrethroid resistance, application of alternative …

Pyrethroid resistance in the dengue vector Aedes aegypti in Southeast Asia: present situation and prospects for management

ZH Amelia-Yap, CD Chen, M Sofian-Azirun, VL Low - Parasites & vectors, 2018‏ - Springer
Human arboviral diseases transmitted by Aedes aegypti such as dengue, Zika, chikungunya
and yellow fever remain global public health threats to date. Of these diseases, dengue …

Amplification of a Cytochrome P450 Gene Is Associated with Resistance to Neonicotinoid Insecticides in the Aphid Myzus persicae

AM Puinean, SP Foster, L Oliphant, I Denholm… - PLOS …, 2010‏ - journals.plos.org
The aphid Myzus persicae is a globally significant crop pest that has evolved high levels of
resistance to almost all classes of insecticide. To date, the neonicotinoids, an economically …

Cytochrome P450-based metabolic insecticide resistance in Anopheles and Aedes mosquito vectors: Muddying the waters

J Vontas, E Katsavou, K Mavridis - Pesticide biochemistry and physiology, 2020‏ - Elsevier
Despite the substantial progress achieved in the characterization of cytochrome P450 (CYP)-
based resistance mechanisms in mosquitoes, a number of questions remain unanswered …