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The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasis
Y Huang, W Hong, X Wei - Journal of hematology & oncology, 2022 - Springer
Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic
development and tissue regeneration. However, aberrant reactivation of EMT is associated …
development and tissue regeneration. However, aberrant reactivation of EMT is associated …
Mechanical regulation of chromatin and transcription
Cells and tissues generate and are exposed to various mechanical forces that act across a
range of scales, from tissues to cells to organelles. Forces provide crucial signals to inform …
range of scales, from tissues to cells to organelles. Forces provide crucial signals to inform …
Epithelial-mesenchymal plasticity in cancer progression and metastasis
W Lu, Y Kang - Developmental cell, 2019 - cell.com
Epithelial-to-mesenchymal transition (EMT) and its reversed process, mesenchymal-to-
epithelial transition (MET), are fundamental processes in embryonic development and tissue …
epithelial transition (MET), are fundamental processes in embryonic development and tissue …
EMT factors and metabolic pathways in cancer
The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …
Molecular mechanisms of epithelial–mesenchymal transition
The transdifferentiation of epithelial cells into motile mesenchymal cells, a process known as
epithelial–mesenchymal transition (EMT), is integral in development, wound healing and …
epithelial–mesenchymal transition (EMT), is integral in development, wound healing and …
Epithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities
Epithelial–mesenchymal transition (EMT) is a program wherein epithelial cells lose their
junctions and polarity while acquiring mesenchymal properties and invasive ability …
junctions and polarity while acquiring mesenchymal properties and invasive ability …
Aberrant regulation and function of microRNAs in cancer
Malignant neoplasms are consistently among the top four leading causes of death in all age
groups in the United States, despite a concerted effort toward develo** novel therapeutic …
groups in the United States, despite a concerted effort toward develo** novel therapeutic …
The role of EMT and MET in cancer dissemination
J Banyard, DR Bielenberg - Connective tissue research, 2015 - Taylor & Francis
Metastatic cancer cells are lethal. Understanding the molecular mechanisms that bolster the
conversion from benign to malignant progression is key for treating these heterogeneous …
conversion from benign to malignant progression is key for treating these heterogeneous …
Regulation of breast cancer metastasis signaling by miRNAs
Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …
The regulatory role of microRNAs in EMT and cancer
A Zaravinos - Journal of oncology, 2015 - Wiley Online Library
The epithelial to mesenchymal transition (EMT) is a powerful process in tumor invasion,
metastasis, and tumorigenesis and describes the molecular reprogramming and phenotypic …
metastasis, and tumorigenesis and describes the molecular reprogramming and phenotypic …