Cardiovascular diseases have become a serious threat to human health now. With the rapid
development of computer technology and medical imaging technology, the method of …

More and more frequently, computational biomechanics deals with problems where the
portion of physical reality to be modeled spans over such a large range of spatial and …

The human brain is possibly the most complex organ in existence. This complexity means
that it is capable of great feats, yet has ensured that it remains surprisingly poorly …

Objective. Dynamic cerebral autoregulation (dCA) is a well-established mechanism that acts
to maintain cerebral blood flow (CBF) reasonably constant in response to short-term …

Cardiopulmonary bypass (CPB) procedure is employed to repair most congenital heart
defects (CHD). Cannulation is a critical component of this procedure where the location and …

Cerebral blood flow velocity (CBFV) is an important parameter for study of cerebral
hemodynamics. However, a simple and highly similar mathematical model has not yet been …

Neurological complications often occur during cardiopulmonary bypass (CPB).
Hypoperfusion of brain tissue due to diminished cerebral autoregulation (CA) and …

Left ventricular stroke work is an important prognostic marker to analyze cardiac function.
Standard values for children are, however, missing. For clinicians, standards can help to …

This thesis is a computational and experimental study of gaseous and solid emboli entering
the body during heart surgery. By incorporating a multi-patient simulation, the research …

It has been shown that left ventricular assist devices (LVADs) increase the survival rate in
end‐stage heart failure patients. However, there is an ongoing demand for an increased …