Kidney fibrosis: from mechanisms to therapeutic medicines
R Huang, P Fu, L Ma - Signal Transduction and Targeted Therapy, 2023 - nature.com
Chronic kidney disease (CKD) is estimated to affect 10–14% of global population. Kidney
fibrosis, characterized by excessive extracellular matrix deposition leading to scarring, is a …
fibrosis, characterized by excessive extracellular matrix deposition leading to scarring, is a …
Engineered exosomes from different sources for cancer-targeted therapy
M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - Signal transduction and …, 2023 - nature.com
Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …
Polydopamine nanoparticles targeting ferroptosis mitigate intervertebral disc degeneration via reactive oxygen species depletion, iron ions chelation, and GPX4 …
X Yang, Y Chen, J Guo, J Li, P Zhang… - Advanced …, 2023 - Wiley Online Library
Intervertebral disc degeneration (IVDD)‐induced lower back pain (LBP) is a common
problem worldwide. The underlying mechanism is partially accredited to ferroptosis, based …
problem worldwide. The underlying mechanism is partially accredited to ferroptosis, based …
Intelligent Micro‐/Nanorobots for Cancer Theragnostic
Cancer is one of the most intractable diseases owing to its high mortality rate and lack of
effective diagnostic and treatment tools. Advancements in micro‐/nanorobot (MNR)‐assisted …
effective diagnostic and treatment tools. Advancements in micro‐/nanorobot (MNR)‐assisted …
Recent progress in exosome research: isolation, characterization and clinical applications
X Wang, J **a, L Yang, J Dai, L He - Cancer Gene Therapy, 2023 - nature.com
Exosomes, a kind of nano-vesicles released by various cell types, carry a variety of “cargos”
including proteins, RNAs, DNAs and lipids. There is substantial evidence that exosomes are …
including proteins, RNAs, DNAs and lipids. There is substantial evidence that exosomes are …
Targeted therapy for inflammatory diseases with mesenchymal stem cells and their derived exosomes: from basic to clinics
S Wang, B Lei, E Zhang, P Gong, J Gu… - International Journal …, 2022 - Taylor & Francis
Inflammation is a beneficial and physiological process, but there are a number of
inflammatory diseases which have detrimental effects on the body. In addition, the drugs …
inflammatory diseases which have detrimental effects on the body. In addition, the drugs …
Advancements in cell membrane camouflaged nanoparticles: a bioinspired platform for cancer therapy
The idea of employing natural cell membranes as a coating medium for nanoparticles (NPs)
endows man-made vectors with natural capabilities and benefits. In addition to retaining the …
endows man-made vectors with natural capabilities and benefits. In addition to retaining the …
Novel tumor-targeting nanoparticles for cancer treatment—A review
Being one of the leading causes of death and disability worldwide, cancer represents an
ongoing interdisciplinary challenge for the scientific community. As currently used treatments …
ongoing interdisciplinary challenge for the scientific community. As currently used treatments …
[HTML][HTML] Small extracellular vesicles: non-negligible vesicles in tumor progression, diagnosis, and therapy
X Zhou, Y Jia, C Mao, S Liu - Cancer Letters, 2024 - Elsevier
Small extracellular vesicles (sEVs) such as exosomes are nanoscale membranous particles
(< 200 nm) that have emerged as crucial targets for liquid biopsy and as promising drug …
(< 200 nm) that have emerged as crucial targets for liquid biopsy and as promising drug …
[HTML][HTML] Molecular targets, therapeutic agents and multitasking nanoparticles to deal with cancer stem cells: A narrative review
There is increasing evidence that malignant tumors are initiated and maintained by a sub-
population of tumor cells that have similar biological properties to normal adult stem cells …
population of tumor cells that have similar biological properties to normal adult stem cells …