[HTML][HTML] Viral factors in modulation of host immune response: A route to novel antiviral agents and new therapeutic approaches

O Tarasova, A Petrou, SM Ivanov, A Geronikaki… - International Journal of …, 2024‏ - mdpi.com
Viruses utilize host cells at all stages of their life cycle, from the transcription of genes and
translation of viral proteins to the release of viral copies. The human immune system …

Identification of potential inhibitors for drug-resistant EGFR mutations in non-small cell lung cancer using whole exome sequencing data

N Nagarajan, C Guda - Frontiers in Pharmacology, 2024‏ - frontiersin.org
Epidermal growth factor receptor (EGFR) gene mutations are prevalent in about 50% of lung
adenocarcinoma patients. Highly effective tyrosine kinase inhibitors (TKIs) targeting the …

Enzymes and enzyme inhibitors—applications in medicine and diagnosis

A Geronikaki, PT Eleutheriou - International Journal of Molecular …, 2023‏ - mdpi.com
The first paper focused on the maintenance of MBCOMT's stability in situations where the
protein needs to be stored for long periods of time. Membrane-bound catechol-O …

Molecular structure, spectral analysis and chemical activity of sabizabulin: A computational study

A Dhasmana, AK Mishra, UB Khoja, S Mishra - Journal of Molecular …, 2023‏ - Elsevier
In this study, a detailed computational spectroscopic investigation of sabizabulin, a small
molecule known as a tubulin inhibitor with potential antineoplastic, antiviral, and anti …

Nitazoxanide and azithromycin for the early treatment of COVID‐19: A multi‐spectroscopic, biochemical and computational drug–drug interaction study

SA Ali, M Abid, A Ahmed, A Wadood… - Journal of the Chinese …, 2023‏ - Wiley Online Library
Herein, we present an experimental and theoretical drug–drug interaction study between
nitazoxanide (NTZ) and azithromycin (AZT) in an aqueous solution. Interaction was studied …