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Models of cardiac tissue electrophysiology: progress, challenges and open questions
Models of cardiac tissue electrophysiology are an important component of the Cardiac
Physiome Project, which is an international effort to build biophysically based multi-scale …
Physiome Project, which is an international effort to build biophysically based multi-scale …
Coupling multi-physics models to cardiac mechanics
We outline and review the mathematical framework for representing mechanical deformation
and contraction of the cardiac ventricles, and how this behaviour integrates with other …
and contraction of the cardiac ventricles, and how this behaviour integrates with other …
Three-dimensional transmural organization of perimysial collagen in the heart
There is strong support for the view that the ventricular myocardium has a laminar
organization in which myocytes are grouped into branching layers separated by cleavage …
organization in which myocytes are grouped into branching layers separated by cleavage …
Three-dimensional virtual histology enabled through cytoplasm-specific X-ray stain for microscopic and nanoscopic computed tomography
Many histological methods require staining of the cytoplasm, which provides instrumental
details for diagnosis. One major limitation is the production of 2D images obtained by …
details for diagnosis. One major limitation is the production of 2D images obtained by …
Three distinct directions of intramural activation reveal nonuniform side-to-side electrical coupling of ventricular myocytes
Background—The anisotropy of cardiac tissue is a key determinant of 3D electric
propagation and the stability of activation wave fronts in the heart. The electric properties of …
propagation and the stability of activation wave fronts in the heart. The electric properties of …
Simulation of oxygen transport and estimation of tissue perfusion in extensive microvascular networks: Application to cerebral cortex
Advanced imaging techniques have made available extensive three-dimensional
microvascular network structures. Simulation of oxygen transport by such networks requires …
microvascular network structures. Simulation of oxygen transport by such networks requires …
[HTML][HTML] Imaging heart development using high-resolution episcopic microscopy
TJ Mohun, WJ Weninger - Current opinion in genetics & development, 2011 - Elsevier
Development of the heart in vertebrate embryos is a complex process in which the organ is
continually remodelled as chambers are formed, valves sculpted and connections …
continually remodelled as chambers are formed, valves sculpted and connections …
High-contrast X-ray micro-radiography and micro-CT of ex-vivo soft tissue murine organs utilizing ethanol fixation and large area photon-counting detector
Using dedicated contrast agents high-quality X-ray imaging of soft tissue structures with
isotropic micrometre resolution has become feasible. This technique is frequently titled as …
isotropic micrometre resolution has become feasible. This technique is frequently titled as …
Estimation of blood flow rates in large microvascular networks
Please cite this paper as: Fry BC, Lee J, Smith NP, Secomb TW. Estimation of blood flow
rates in large microvascular networks. Microcirculation 19: 530–538, 2012. Abstract …
rates in large microvascular networks. Microcirculation 19: 530–538, 2012. Abstract …
Three-dimensional myoarchitecture of the lower esophageal sphincter and esophageal hiatus using optical sectioning microscopy
Studies to date have failed to reveal the anatomical counterpart of the lower esophageal
sphincter (LES). We assessed the LES and esophageal hiatus morphology using a block …
sphincter (LES). We assessed the LES and esophageal hiatus morphology using a block …