Functional analysis of circulating tumour cells: the KEY to understand the biology of the metastatic cascade
Metastasis formation is the main cause of cancer-related death in patients with solid
tumours. At the beginning of this process, cancer cells escape from the primary tumour to the …
tumours. At the beginning of this process, cancer cells escape from the primary tumour to the …
The metastatic cascade as the basis for liquid biopsy development
The metastatic cascade describes the process whereby aggressive cancer cells leave the
primary tumor, travel through the bloodstream, and eventually reach distant organs to …
primary tumor, travel through the bloodstream, and eventually reach distant organs to …
Identifying key questions in the ecology and evolution of cancer
The application of evolutionary and ecological principles to cancer prevention and
treatment, as well as recognizing cancer as a selection force in nature, has gained impetus …
treatment, as well as recognizing cancer as a selection force in nature, has gained impetus …
Do malignant cells sleep at night?
Biological rhythms regulate the biology of most, if not all living creatures, from whole
organisms to their constitutive cells, their microbiota, and also parasites. Here, we present …
organisms to their constitutive cells, their microbiota, and also parasites. Here, we present …
The genomic processes of biological invasions: From invasive species to cancer metastases and back again
The concept of invasion is useful across a broad range of contexts, spanning from the fine
scale landscape of cancer tumors up to the broader landscape of ecosystems. Invasion …
scale landscape of cancer tumors up to the broader landscape of ecosystems. Invasion …
Evo-devo perspectives on cancer
AM Nedelcu - Essays in Biochemistry, 2022 - portlandpress.com
The integration of evolutionary and developmental approaches into the field of evolutionary
developmental biology has opened new areas of inquiry—from understanding the evolution …
developmental biology has opened new areas of inquiry—from understanding the evolution …
Tumors are evolutionary island-like ecosystems
Integration of ecological and evolutionary features has begun to understand the interplay of
tumor heterogeneity, microenvironment, and metastatic potential. Develo** a theoretical …
tumor heterogeneity, microenvironment, and metastatic potential. Develo** a theoretical …
Modeling cancer's ecological and evolutionary dynamics
In this didactic paper, we present a theoretical modeling framework, called the G-function,
that integrates both the ecology and evolution of cancer to understand oncogenesis. The G …
that integrates both the ecology and evolution of cancer to understand oncogenesis. The G …
Does cancer biology rely on Parrondo's principles?
Simple Summary Parrondo's paradox, whereby losing strategies or deleterious effects can
combine to provide a winning outcome, has been increasingly applied by biologists to …
combine to provide a winning outcome, has been increasingly applied by biologists to …
The conditional defector strategies can violate the most crucial supporting mechanisms of cooperation
AM Ibrahim - Scientific Reports, 2022 - nature.com
Cooperation is essential for all domains of life. Yet, ironically, it is intrinsically vulnerable to
exploitation by cheats. Hence, an explanatory necessity spurs many evolutionary biologists …
exploitation by cheats. Hence, an explanatory necessity spurs many evolutionary biologists …