Do alkaline phosphatases have great potential in the diagnosis, prognosis, and treatment of tumors?

T Jiang, Q Zeng, J He - Translational Cancer Research, 2023 - pmc.ncbi.nlm.nih.gov
Alkaline phosphatase (ALP) is a group of enzymes that catalyze hydrolysis of phosphate
esters at an alkaline pH, resulting in the generation of inorganic phosphate. These enzymes …

[HTML][HTML] A faecal microbiota signature with high specificity for pancreatic cancer

E Kartal, TSB Schmidt, E Molina-Montes… - Gut, 2022 - gut.bmj.com
Background Recent evidence suggests a role for the microbiome in pancreatic ductal
adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and …

Prognostic value of alkaline phosphatase and bone-specific alkaline phosphatase in breast cancer: A systematic review and meta-analysis

C Jiang, F Hu, X **a, X Guo - The International Journal of …, 2023 - journals.sagepub.com
Numerous studies have reported the clinical value of alkaline phosphatase (ALP) and its
bone-specific isoforms (bone-specific alkaline phosphatase (BAP)) in breast cancer. The …

Inflammasomes in breast cancer: the ignition spark of progression and resistance?

S Elgohary, HM El Tayebi - Expert Reviews in Molecular Medicine, 2023 - cambridge.org
Inflammation and immune evasion are major key players in breast cancer (BC) progression.
Recently, the FDA approved the use of anti-programmed death-ligand 1 antibody (anti-PD …

Role of the gut microbiota in tumorigenesis and treatment

Q Liu, Y Yang, M Pan, F Yang, Y Yu, Z Qian - Theranostics, 2024 - pmc.ncbi.nlm.nih.gov
The gut microbiota is a crucial component of the intricate microecosystem within the human
body that engages in interactions with the host and influences various physiological …

Association between alkaline phosphatase levels and mortality in Chinese patients with colorectal cancer with liver metastases: a retrospective cohort study

ZX Liu, ZQ Zhang, GF Yu, MJ Mo… - Therapeutic …, 2025 - journals.sagepub.com
Background: Alkaline phosphatase (ALP) is a potential cancer biomarker. However, its
prognostic value in patients with colorectal liver metastasis remains unclear. Objectives: This …

Clinical significance of preoperative albumin and alkaline phosphatase in colorectal cancer: a systematic review and meta-analysis

D Xu, Q Zhao - American Journal of Translational Research, 2024 - pmc.ncbi.nlm.nih.gov
Objective: To investigate the association between preoperative serum levels of albumin
(ALB) and alkaline phosphatase (ALP) with postoperative outcome in colorectal cancer …

前列腺癌早期筛查风险预测模型的建立与验证研究

**宏基, 赵晓龙, 胡伟, **东晖, 王安辉, 秦卫军 - **全科医学, 2024 - chinagp.net
背景前列腺癌作为常见的恶性肿瘤, 威胁中老年男性生命健康, 其预后与初诊时肿瘤级别与分期
密切相关. 前列腺特异性抗原(PSA) 是前列腺癌早期筛查的重要分子, 但非肿瘤负荷的前列腺 …

Triose phosphate isomerase 1 in serum of women with breast cancer

OA Jwameer, EA Hassan, FM Al-Abady - Revista de Senología y Patología …, 2025 - Elsevier
Abstract Introduction Triosephosphate isomerase 1 (TPI1) plays a role in various biological
processes, specifically in the development of the metastatic phenotype, and is recognized as …

Construction of a breast cancer predictive nomogram based on diverse cell death methods and reveal tumor microenvironment characterization

R Wu, Z Wang, C Dong, Y Liu, L Chen - bioRxiv, 2024 - biorxiv.org
Objective To develop a robust predictive model and nomogram for breast cancer (BC) linked
to genes associated with diverse cell death methods. Methods The prognostic model was …