Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories

T Hainmueller, M Bartos - Nature Reviews Neuroscience, 2020 - nature.com
The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

On the integration of space, time, and memory

H Eichenbaum - Neuron, 2017 - cell.com
The hippocampus is famous for map** locations in spatially organized environments, and
several recent studies have shown that hippocampal networks also map moments in …

Hippocampal sharp wave‐ripple: A cognitive biomarker for episodic memory and planning

G Buzsáki - Hippocampus, 2015 - Wiley Online Library
Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

A dedicated population for reward coding in the hippocampus

JL Gauthier, DW Tank - Neuron, 2018 - cell.com
The hippocampus plays a critical role in goal-directed navigation. Across different
environments, however, hippocampal maps are randomized, making it unclear how goal …

The 3D OrbiSIMS—label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power

MK Passarelli, A Pirkl, R Moellers, D Grinfeld… - Nature …, 2017 - nature.com
We report the development of a 3D OrbiSIMS instrument for label-free biomedical imaging. It
combines the high spatial resolution of secondary ion mass spectrometry (SIMS; under 200 …

Resolving the neural circuits of anxiety

GG Calhoon, KM Tye - Nature neuroscience, 2015 - nature.com
Although anxiety disorders represent a major societal problem demanding new therapeutic
targets, these efforts have languished in the absence of a mechanistic understanding of this …

Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

D Franjic, M Skarica, S Ma, JI Arellano… - Neuron, 2022 - cell.com
The hippocampal-entorhinal system supports cognitive functions, has lifelong neurogenic
capabilities in many species, and is selectively vulnerable to Alzheimer's disease. To …

The role of hippocampal replay in memory and planning

HF Ólafsdóttir, D Bush, C Barry - Current Biology, 2018 - cell.com
The mammalian hippocampus is important for normal memory function, particularly memory
for places and events. Place cells, neurons within the hippocampus that have spatial …

The hippocampus

JJ Knierim - Current Biology, 2015 - cell.com
The hippocampus is one of the most thoroughly investigated structures in the brain. Ever
since the 1957 report of the case study HM, who famously lost the ability to form new …

Distinct tau prion strains propagate in cells and mice and define different tauopathies

DW Sanders, SK Kaufman, SL DeVos, AM Sharma… - Neuron, 2014 - cell.com
Prion-like propagation of tau aggregation might underlie the stereotyped progression of
neurodegenerative tauopathies. True prions stably maintain unique conformations (" …