The future of brain circuit-targeted therapeutics

SH Siddiqi, S Khosravani, JD Rolston… - …, 2024 - nature.com
The principle of targeting brain circuits has drawn increasing attention with the growth of
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain …

Targeting symptom-specific networks with transcranial magnetic stimulation

SH Siddiqi, MD Fox - Biological Psychiatry, 2024 - Elsevier
Increasing evidence suggests that the clinical effects of transcranial magnetic stimulation are
target dependent. Within any given symptom, precise targeting of specific brain circuits may …

[HTML][HTML] Neuronavigation maximizes accuracy and precision in TMS positioning: evidence from 11,230 distance, angle, and electric field modeling measurements

KA Caulfield, HH Fleischmann, CE Cox, JP Wolf… - Brain stimulation, 2022 - Elsevier
Background Researchers and clinicians have traditionally relied on elastic caps with
markings to reposition the transcranial magnetic stimulation (TMS) coil between trains and …

[HTML][HTML] Dosing transcranial magnetic stimulation in major depressive disorder: relations between number of treatment sessions and effectiveness in a large patient …

TM Hutton, ST Aaronson, LL Carpenter, K Pages… - Brain Stimulation, 2023 - Elsevier
Background The number of sessions in an acute TMS course for major depressive disorder
(MDD) is greater than in the earlier randomized controlled trials. Objective To compare …

A meta-analysis of transcranial magnetic stimulation in obsessive-compulsive disorder

ER Steuber, JF McGuire - Biological Psychiatry: Cognitive Neuroscience …, 2023 - Elsevier
Background Obsessive-compulsive disorder (OCD) is a debilitating illness with substantial
morbidity. Although pharmacological and behavioral evidence–based treatments have …

Electric-field-based dosing for TMS

O Numssen, P Kuhnke, K Weise… - Imaging …, 2024 - direct.mit.edu
Transcranial magnetic stimulation (TMS) is an invaluable non-invasive brain stimulation
(NIBS) technique to modulate cortical activity and behavior, but high within-and between …

Practice makes plasticity: 10-Hz rTMS enhances LTP-like plasticity in musicians and athletes

J Kweon, MM Vigne, RN Jones, LL Carpenter… - Frontiers in Neural …, 2023 - frontiersin.org
Motor skill learning has been linked to functional and structural changes in the brain.
Musicians and athletes undergo intensive motor training through the practice of an …

Pharmacological adjuncts and transcranial magnetic stimulation-induced synaptic plasticity: a systematic review

MN Sohn, JC Brown, P Sharma, U Ziemann… - Journal of Psychiatry and …, 2024 - jpn.ca
Background: Transcranial magnetic stimulation (TMS) is a noninvasive neurostimulation
modality that has been used to study human synaptic plasticity. Leveraging work in ex vivo …

Multiscale network neuroscience in neuro-oncology: How tumors, brain networks, and behavior connect across scales

DA Maas, L Douw - Neuro-Oncology Practice, 2023 - academic.oup.com
Network neuroscience refers to the investigation of brain networks across different spatial
and temporal scales, and has become a leading framework to understand the biology and …

[HTML][HTML] A new angle on transcranial magnetic stimulation coil orientation: A targeted narrative review

A Cerins, EHX Thomas, T Barbour, JJ Taylor… - Biological Psychiatry …, 2024 - Elsevier
Transcranial magnetic stimulation (TMS) is used to treat several neuropsychiatric disorders
including depression, where it is effective in approximately half of patients for whom …