Neurophysiology of dystonia: the role of inhibition

M Hallett - Neurobiology of disease, 2011 - Elsevier
The pathophysiology of dystonia has been best studied in patients with focal hand dystonia.
A loss of inhibitory function has been demonstrated at spinal, brainstem and cortical levels …

Consensus paper on short-interval intracortical inhibition and other transcranial magnetic stimulation intracortical paradigms in movement disorders

A Berardelli, G Abbruzzese, R Chen, M Orth… - Brain stimulation, 2008 - Elsevier
In this article we reviewed the results obtained with the technique of paired-pulse
transcranial magnetic stimulation (TMS) in normal subjects and in patients with movement …

The role of contralesional dorsal premotor cortex after stroke as studied with concurrent TMS-fMRI

S Bestmann, O Swayne, F Blankenburg… - Journal of …, 2010 - jneurosci.org
Contralesional dorsal premotor cortex (cPMd) may support residual motor function following
stroke. We performed two complementary experiments to explore how cPMd might perform …

Comparison of “standard” and “navigated” procedures of TMS coil positioning over motor, premotor and prefrontal targets in patients with chronic pain and depression

R Ahdab, SS Ayache, P Brugières, C Goujon… - Neurophysiologie …, 2010 - Elsevier
Since about 15 years, transcranial magnetic stimulation (TMS) is used as a technique to
investigate the function of specific cortical regions. Single pulse TMS studies have targeted …

Inter-individual variability in cortical excitability and motor network connectivity following multiple blocks of rTMS

C Nettekoven, LJ Volz, M Leimbach, EM Pool… - Neuroimage, 2015 - Elsevier
The responsiveness to non-invasive neuromodulation protocols shows high inter-individual
variability, the reasons of which remain poorly understood. We here tested whether the …

Hyperkinetic disorders and loss of synaptic downscaling

P Calabresi, A Pisani, J Rothwell, V Ghiglieri… - Nature …, 2016 - nature.com
Recent clinical and preclinical studies have shown that hyperkinetic disorders such as
Huntington's disease, dystonia and l-DOPA-induced dyskinesia in Parkinson's disease are …

Network connectivity and individual responses to brain stimulation in the human motor system

L Cárdenas-Morales, LJ Volz, J Michely… - Cerebral …, 2014 - academic.oup.com
The mechanisms driving cortical plasticity in response to brain stimulation are still
incompletely understood. We here explored whether neural activity and connectivity in the …

TMS investigations into the task-dependent functional interplay between human posterior parietal and motor cortex

G Koch, JC Rothwell - Behavioural brain research, 2009 - Elsevier
Transcranial magnetic stimulation (TMS) can be used in two different ways to investigate the
contribution of cortical areas involved in grasp/reach movements in humans. It can produce …

Is this dystonia?

A Albanese, S Lalli - Movement disorders, 2009 - Wiley Online Library
Torsion dystonia is characterized by sustained muscle contractions causing twisting and
repetitive movements and abnormal postures. The diagnosis can be made difficult, delayed …

Restoration of motor inhibition through an abnormal premotor‐motor connection in dystonia

YZ Huang, JC Rothwell, CS Lu, JJ Wang… - Movement …, 2010 - Wiley Online Library
To clarify the rationale for using rTMS of dorsal premotor cortex (PMd) to treat dystonia, we
examined how the motor system reacts to an inhibitory form of rTMS applied to the PMd in …