Human cystatin C induces the disaggregation process of selected amyloid beta peptides: a structural and kinetic view
Neurodegenerative diseases, such as Alzheimer's disease (AD) and various types of
amyloidosis, are incurable; therefore, understanding the mechanisms of amyloid …
amyloidosis, are incurable; therefore, understanding the mechanisms of amyloid …
Guluronic acid disaccharide inhibits reactive oxygen species production and amyloid-β oligomer formation
H Shen, W Liu, Y Dou, Y Lu, C Zhang, X Wang… - Biochemical and …, 2024 - Elsevier
In general, Cu (II) is the critical factor in catalyzing reactive oxygen species (ROS) production
and accelerating amyloid-β (Aβ) oligomer formation in Alzheimer's disease (AD). Natural …
and accelerating amyloid-β (Aβ) oligomer formation in Alzheimer's disease (AD). Natural …
Structural Reorganization Mechanism of the Aβ42 Fibril Mediated by N-Substituted Oligopyrrolamide ADH-353
The inhibition of amyloid-β (Aβ) fibrillation and clearance of Aβ aggregates have emerged
as a potential pharmacological strategy to alleviate Aβ aggregate-induced neurotoxicity in …
as a potential pharmacological strategy to alleviate Aβ aggregate-induced neurotoxicity in …
Identification of vilazodone as a novel plasminogen activator inhibitor to overcome Alzheimer's disease through virtual screening, molecular dynamics simulation, and …
W Sun, X Sheng, P Li, R Li, Z Guo, H Lin… - Archiv der …, 2024 - Wiley Online Library
Urokinase‐type plasminogen activator (PLAU), a member of the S1 serine peptidase family
in Clan PA, plays a crucial role in the conversion of plasminogen into active plasmin …
in Clan PA, plays a crucial role in the conversion of plasminogen into active plasmin …