Inter-individual variability in drug response, be it efficacy or safety, is common and likely to
become an increasing problem globally given the growing elderly population requiring …

With growing global concern regarding medication-related harm, WHO launched a global
patient safety challenge, Medication Without Harm, in March, 2017. Multimorbidity …

Background A third of older people take five or more regular medications (polypharmacy).
Conducting medication reviews in primary care is key to identify and reduce/stop …

Background Multimorbidity, the presence of more than one condition in a single individual, is
a global health issue in primary care. Multimorbid patients tend to have a poor quality of life …

Background: Older people experience greater morbidity with a corresponding increase in
medication use resulting in a potentially higher risk of adverse drug reactions (ADRs) …

Background: An international consensus list of potentially clinically significant drug-drug
interactions (DDIs) in older people has been recently validated. Our objective was to …

Adverse drug reactions (ADRs) account for a large proportion of hospitalizations among
adults and are more common in multimorbid patients, worsening clinical outcomes and …

Objectives To quantify prevalence, harms, and NHS costs in England of problematic oral
non-steroidal anti-inflammatory drug (NSAID) prescribing in high risk groups. Design …

Cardiovascular disease remains a leading cause of both morbidity and mortality worldwide.
It is widely accepted that both concomitant medications (drug–drug interactions, DDIs) and …

Artificial intelligence (AI) platforms have emerged as pivotal tools in genetics and molecular
medicine, as in many other fields. The growth in patient data, identification of new diseases …