Bias caused by sampling error in meta-analysis with small sample sizes

L Lin - PloS one, 2018‏ - journals.plos.org
Background Meta-analyses frequently include studies with small sample sizes. Researchers
usually fail to account for sampling error in the reported within-study variances; they model …

Cardiac computed tomography versus transesophageal echocardiography for the detection of left atrial appendage thrombus: a systemic review and meta‐analysis

S Yu, H Zhang, H Li - Journal of the American Heart Association, 2021‏ - ahajournals.org
Background Transesophageal echocardiography (TEE) has been considered the gold
standard for left atrial appendage (LAA) thrombus detection. Nevertheless, TEE may …

Meta-analysis of proportions using generalized linear mixed models

L Lin, H Chu - Epidemiology, 2020‏ - journals.lww.com
Epidemiologic research often involves meta-analyses of proportions. Conventional two-step
methods first transform each study's proportion and subsequently perform a meta-analysis …

Methods for deriving risk difference (absolute risk reduction) from a meta-analysis

MH Murad, Z Wang, Y Zhu, S Saadi, H Chu, L Lin - bmj, 2023‏ - bmj.com
Trading off benefits and harms requires knowledge of the absolute risk reduction or risk
difference, making risk difference a critical measure for decision making. The confidence …

Performing arm-based network meta-analysis in R with the pcnetmeta package

L Lin, J Zhang, JS Hodges, H Chu - Journal of statistical software, 2017‏ - jstatsoft.org
Network meta-analysis is a powerful approach for synthesizing direct and indirect evidence
about multiple treatment comparisons from a collection of independent studies. At present …

Assessment of serological responses following vaccination campaigns with type 2 novel oral polio vaccine: a population-based study in Tajikistan in 2021

A Mirzoev, GR Macklin, Y Zhang, BA Mainou… - The Lancet Global …, 2022‏ - thelancet.com
Background Novel oral poliovirus vaccine type 2 (nOPV2) was used to control an outbreak
of type 2 circulating vaccine derived poliovirus (cVDPV2) in Tajikistan, in 2021. We …

Hierarchical models that address measurement error are needed to evaluate the correlation between treatment effect and control group event rate

MH Murad, H Chu, Z Wang, L Lin - Journal of Clinical Epidemiology, 2024‏ - Elsevier
Objective To apply a hierarchical model (HM) that addresses measurement error in
regression of the treatment effect on the control group event rate (CR). We compare HM to …

The normality assumption on between-study random effects was questionable in a considerable number of Cochrane meta-analyses

Z Liu, FM Al Amer, M **ao, C Xu, L Furuya-Kanamori… - BMC medicine, 2023‏ - Springer
Background Studies included in a meta-analysis are often heterogeneous. The traditional
random-effects models assume their true effects to follow a normal distribution, while it is …

Exclusion of studies with no events in both arms in meta-analysis impacted the conclusions

C Xu, L Li, L Lin, H Chu, L Thabane, K Zou… - Journal of clinical …, 2020‏ - Elsevier
Objectives Classical meta-analyses routinely treated studies with no events in both arms
noninformative and excluded them from analyses. This study assessed whether such …

Network meta-analysis of randomized clinical trials: reporting the proper summaries

J Zhang, BP Carlin, JD Neaton, GG Soon… - Clinical …, 2014‏ - journals.sagepub.com
Background In the absence of sufficient data directly comparing multiple treatments, indirect
comparisons using network meta-analyses (NMAs) can provide useful information. Under …