Current and emerging biological therapy in adult-onset Still's disease

Y Ma, J Meng, J Jia, M Wang, J Teng, D Zhu… - …, 2021 - academic.oup.com
Adult-onset Still's disease (AOSD) is a rare, but characteristic non-familial, multi-genic
systemic auto-inflammatory disorder, characterized by high spiking fever, salmon-like …

An update on the pathogenic role of neutrophils in systemic juvenile idiopathic arthritis and adult-onset Still's disease

JW Kim, MH Ahn, JY Jung, CH Suh, HA Kim - International Journal of …, 2021 - mdpi.com
Neutrophils are innate immune phagocytes that play a key role in immune defense against
invading pathogens. The main offensive mechanisms of neutrophils are the phagocytosis of …

Ferritin triggers neutrophil extracellular trap-mediated cytokine storm through Msr1 contributing to adult-onset Still's disease pathogenesis

J Jia, M Wang, J Meng, Y Ma, Y Wang, N Miao… - Nature …, 2022 - nature.com
Hyperferritinemic syndrome, an overwhelming inflammatory condition, is characterized by
high ferritin levels, systemic inflammation and multi-organ dysfunction, but the pathogenic …

[HTML][HTML] LCN2 mediates skin inflammation in psoriasis through the SREBP2‒NLRC4 axis

J Ma, J Chen, K Xue, C Yu, E Dang, H Qiao… - Journal of Investigative …, 2022 - Elsevier
Lipocalins are a family of secreted adipokines that regulate cell lipid metabolism and
immune responses. Although we have previously revealed that LCN2 modulates neutrophil …

[HTML][HTML] Enhanced type I interferon signature induces neutrophil extracellular traps enriched in mitochondrial DNA in adult-onset Still's disease

Y Ma, M Wang, J Jia, J Meng, J Teng, D Zhu, H Shi… - Journal of …, 2022 - Elsevier
Adult-onset Still's disease (AOSD) is a rare but clinically well-known auto-inflammatory
disorder. Cytokine storm, the hallmark of AOSD, is mediated by neutrophil hyperactivation …

Adult-onset Still's disease: novel biomarkers of specific subsets, disease activity, and relapsing forms

B Maranini, G Ciancio, M Govoni - International Journal of Molecular …, 2021 - mdpi.com
Adult-onset Still's disease (AOSD) is a systemic inflammatory disease of unknown etiology.
Recent studies have demonstrated that the hallmark of AOSD is a cytokine storm, which is …

Glutathione peroxidase 3 is a novel clinical diagnostic biomarker and potential therapeutic target for neutrophils in rheumatoid arthritis

T Chen, Z Zhou, M Peng, H Hu, R Sun, J Xu… - Arthritis Research & …, 2023 - Springer
Background Neutrophils have a critical role in the pathogenesis of rheumatoid arthritis (RA)
with immune system dysfunction. However, the molecular mechanisms of this process …

Advancing personalised precision treatment for Still's disease based on molecular characteristics and disease progression

Y Shen, J Jia, J Teng, C Yang, Q Hu - The Lancet Rheumatology, 2024 - thelancet.com
Still's disease, a systemic autoinflammatory disorder with a classic multigenetic background,
is characterised by polyarthritis, high-spiking fever, salmon-like evanescent skin rash, and …

[HTML][HTML] Болезнь Стилла взрослых: новые горизонты

ЕЛ Насонов, Е Файст - Научно-практическая ревматология, 2021 - cyberleninka.ru
Болезни Стилла у детей (системный ювенильный идиопатический артрит (ЮИА)) и у
взрослых (болезнь Стилла взрослых (БСВ)) рассматриваются как системные …

Bibliometrics analysis on the research status and trends of adult-onset Still's disease: 1921-2021

A Qin, J Sun, C Gao, C Li - Frontiers in Immunology, 2022 - frontiersin.org
Objectives The aim of this research is to discuss the research status, hotspots, frontiers and
development trends in the field of adult-onset Still's disease (AOSD) based on bibliometrics …