Challenges and opportunities of functionalized cucurbiturils for biomedical applications

H Yin, Q Cheng, D Bardelang, R Wang - JACS Au, 2023 - ACS Publications
Cucurbit [n] uril (CB [n]) macrocycles (especially CB [5] to CB [8]) have shown exceptional
attributes since their discovery in 2000. Their stability, water solubility, responsiveness to …

Recent advances and prospects in organic molecule-based phototheranostic agents for enhanced cancer phototherapy

YY Zhao, H Kim, VN Nguyen, S Jang, WJ Jang… - Coordination Chemistry …, 2024 - Elsevier
Phototherapy, includes photodynamic therapy (PDT) and photothermal therapy (PTT), which
combine light with an adequate wavelength and a chemical phototheranostic agent in the …

In situ hypoxia-induced supramolecular perylene diimide radical anions in tumors for photothermal therapy with improved specificity

H Wang, KF Xue, Y Yang, H Hu, JF Xu… - Journal of the American …, 2022 - ACS Publications
Considering that hypoxia is closely associated with tumor proliferation, invasion, metastasis,
and drug resistance, it is of great significance to overcome hypoxia in tumor treatment …

Cucurbit [7] uril‐mediated organ‐specific delivery of ultrasmall NIR‐II luminescent gold nanocarriers for therapy of acute kidney injury

K He, YF Ding, Z Zhao, B Liu, W Nie… - Advanced Functional …, 2024 - Wiley Online Library
The design of nanocarriers that selectively target the liver or kidney is a significant challenge
in drug delivery due to the diverse physiological structures and inherent characteristics, as …

Regulation of Cell Membrane Potential through Supramolecular System for Activating Calcium Ion Channels

G Song, B Li, Z Yang, H Lin, J Cheng… - Journal of the …, 2024 - ACS Publications
The regulation of the cell membrane potential plays a crucial role in governing the
transmembrane transport of various ions and cellular life processes. However, in situ and on …

Gene and photothermal combination therapy: principle, materials, and amplified anticancer intervention

F Tang, A Ding, Y Xu, Y Ye, L Li, R **e, W Huang - Small, 2024 - Wiley Online Library
Gene therapy (GT) and photothermal therapy (PTT) have emerged as promising alternatives
to chemotherapy and radiotherapy for cancer treatment, offering noninvasiveness and …

A self-degradable nanostructured phthalocyanine assembly with high photothermal efficacy to enhanced biosecurity in photothermal therapy

YY Zhao, Z Chen, L Zhang, XW Qin, H Liu… - Chemical Engineering …, 2023 - Elsevier
Photothermal therapy (PTT) possesses a great promise for tumor therapy due to its effective
tumor inhibition and minimal invasiveness. Nevertheless, most of organic photothermal …

Polydopamine-doped supramolecular chiral hydrogels for postoperative tumor recurrence inhibition and simultaneously enhanced wound repair

X Wang, B Wu, Y Zhang, X Dou, C Zhao, C Feng - Acta Biomaterialia, 2022 - Elsevier
Cancer recurrence remains a major challenge after primary tumor excision, and the
inflammation of tumor-caused wounds can hinder wound healing and potentially promote …

Targeted delivery and enhanced uptake of chemo-photodynamic nanomedicine for melanoma treatment

X Huang, N Mu, Y Ding, HW Lam, L Yue, C Gao… - Acta Biomaterialia, 2022 - Elsevier
Nanoparticles (NPs) modified with targeting ligands have often shown great potential in
targeted drug delivery for tumor therapy. However, the clearance of NPs by the monocyte …

Begonia-inspired slow photon effect of a photonic crystal for augmenting algae photosynthesis

X Zhou, Y Zhang, H Ding, J Liao, Q Li, Z Gu - ACS nano, 2022 - ACS Publications
Plant photosynthesis is considered to be an environmentally friendly and effective measure
for reducing carbon dioxide levels to meet the global objective of carbon neutrality …