Pattern, frequency and factors associated with inappropriate high dosing in chronic kidney disease patients at a tertiary care hospital in Pakistan

M Hayat, N Ahmad, SLA Khan, S Mohkumuddin… - BMC nephrology, 2023 - Springer
Background Patients with chronic kidney diseases (CKD) are susceptible to the toxic drug
effects if given unadjusted doses. Although Pakistan harbors a high burden of CKD patients …

Renal drug dosage adjustments and adverse drug events in patients with chronic kidney disease admitted to the hospital: a cross-sectional study

Z Očovská, J Procházková, M Maříková… - Expert Opinion on Drug …, 2024 - Taylor & Francis
Background The study aimed to evaluate the agreement of prescribed drug dosages with
renal dosing recommendations and describe adverse drug events (ADEs) contributing to …

Assessment of inappropriate dose adjustment of antimicrobials and other medicines Among chronic kidney disease patients: A multicenter observational study

R Zafar, IU Rehman, Y Shah… - … In Microbes & …, 2023 - journals.hh-publisher.com
Most drugs undergo metabolism and elimination primarily by the kidneys. Consequently,
drug dosages are largely contingent upon kidney function and require careful adjustment in …

Use of antibiotics in patients with chronic kidney disease: evidence from the real world

LF Valladales-Restrepo… - Expert Opinion on …, 2024 - Taylor & Francis
Background Most antibiotics require dose adjustments in patients with chronic kidney
disease (CKD) to avoid accumulation and toxicity. The aim was to characterize the use of …

Impact of pharmacist-led intervention for reducing drug-related problems and improving quality of life among chronic kidney disease patients: A randomized controlled …

R Zafar, IU Rehman, Y Shah, LC Ming, KW Goh… - PloS one, 2025 - journals.plos.org
Introduction Chronic kidney disease (CKD) patients suffer from different comorbid conditions
and are prone toward drug-related problems (DRPs) which affect their clinical parameters as …

Frequency and predictors of inappropriate medication dosages for cardiovascular disease prevention in chronic kidney disease patients: a retrospective cross …

J Jamaluddin, MS Mohamed-Yassin, SN Jamil… - Heliyon, 2023 - cell.com
Patients with chronic kidney disease (CKD) are at increased risk of cardiovascular events.
This study aimed to assess the frequency of inappropriate medication dosages (IMD) for …

Pseudo‐Worsening of Kidney Function Due to Inhibition of Renal Creatinine Secretion: Quality of Information Provided in Prescribing Information/SmPC

MI Sponfeldner, W Andrikyan, R Maas… - Clinical …, 2024 - Wiley Online Library
Determination of serum creatinine concentrations and subsequent calculation of estimated
glomerular filtration rates (eGFR) is a cornerstone of clinical medicine. Crucial clinical …

Navigating nephrology: unveiling pharmacist perspectives on renal dose adjustment in Saudi Arabia–a comprehensive cross-sectional analysis

HM Alosaimi, RA Alwatban… - … Policy and Practice, 2024 - Taylor & Francis
Introduction Chronic kidney disease (CKD) is a major public health concern in Saudi Arabia.
it is pertinent to mention that in the Southwestern region of Saudi Arabia. Hypertension and …

Drug Utilization Evaluation and Impact of Pharmacist Interventions on Optimization of Piperacillin/Tazobactam Use: A Retrospective Analysis and Prospective Audit

S Arain, F Khalawi, SA Parakkal, HS AlHamad… - Antibiotics, 2023 - mdpi.com
(1) Background: Piperacillin/tazobactam is a broad-spectrum antimicrobial encompassing
most Gram-positive and Gram-negative aerobic and anaerobic bacteria. The inappropriate …

[PDF][PDF] Evaluation of carbapenem antimicrobial stewardship program at a tertiary care hospital: A prospective interventional study

F Ali, T Zehra, NA Solangi, KU Makki… - Pak J Pharm …, 2022 - researchgate.net
This study aimed to determine physicians' acceptance rate of the Antimicrobial Stewardship
Program ASP interventions in critically ill patients and to compare the clinical outcomes …