Biomarkers are measurable indicators of a biological state. As our understanding of
diseases meliorates, it is generally accepted that early diagnosis renders the best chance to …

Purpose To provide recommendations on the follow-up and management of patients with
breast cancer who have completed primary therapy with curative intent. Methods To update …

Purpose Prognostic and predictive factors are well established in early-stage breast cancer,
but less is known about which metastatic sites will be affected. Methods Patients with early …

Bone is the most common site to which breast cancer metastasizes. Imaging—by skeletal
scintigraphy, plain radiography, computed tomography, or magnetic resonance imaging—is …

Purpose Most women with breast cancer are diagnosed at an early stage and more than
80% will be long-term survivors. Routine follow-up marks the transition from intensive …

Detection of bone involvement is essential for optimal therapy of oncologic patients. The
purpose of imaging is to identify early bone involvement, to determine the full extent of the …

The idea that somatic ERα mutations could play an important role in the evolution of
hormone-dependent breast cancers was proposed some years ago (Fuqua J Mammary …

Breast cancer is the most common malignancy in women in the United States and is second
only to lung cancer as a cause of cancer death. The overall management of breast cancer …

The recent Institute of Medicine report “From Cancer Patient to Cancer Survivor: Lost in
Transition” recommended the creation of survivorship care plans for patients as they …

Overview These NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for
Breast Cancer are the work of the members of the NCCN Breast Cancer Panel. Categories …