Counteracting Immunosenescence—Which Therapeutic Strategies Are Promising?

C Hieber, S Grabbe, M Bros - Biomolecules, 2023 - mdpi.com
Aging attenuates the overall responsiveness of the immune system to eradicate pathogens.
The increased production of pro-inflammatory cytokines by innate immune cells under basal …

A key driver to promote HCC: cellular crosstalk in tumor microenvironment

P Liu, L Kong, Y Liu, G Li, J **e, X Lu - Frontiers in oncology, 2023 - frontiersin.org
Liver cancer is the third greatest cause of cancer-related mortality, which of the major
pathological type is hepatocellular carcinoma (HCC) accounting for more than 90%. HCC is …

The roles of immunoregulatory networks in severe drug hypersensitivity

YSO Hsu, KL Lu, Y Fu, CW Wang, CW Lu… - Frontiers in …, 2021 - frontiersin.org
The immunomodulatory effects of regulatory T cells (Tregs) and co-signaling receptors have
gained much attention, as they help balance immunogenic and immunotolerant responses …

Qingre lishi decoction ameliorates imiquimod-induced psoriasis-like skin lesions in SKH-1 mice by regulating the Treg-DC-Th17 axis and inhibiting MAPK-mediated …

X Zhu, Q Xu, Z Liu, Z Cao, M Li, J Wei, L Du… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Psoriasis, an immune system disorder, is a chronic
relapsing disease that cannot be cured. Chinese herbal medicine is gradually considered a …

A better understanding of the role of the CTLA–CD80/86 axis in the treatment of autoimmune diseases

Z Darvish, RK Kheder, TA Faraj… - Cell Biochemistry …, 2024 - Wiley Online Library
Autoimmune diseases are diseases in which the regulatory mechanisms of the immune
response are disturbed. As a result, the body loses self‐tolerance. Since one of the main …

Targeting stem cell-derived tissue-associated regulatory T Cells for type 1 diabetes immunotherapy

M Haque, JK Das, X **ong, J Song - Current diabetes reports, 2019 - Springer
Abstract Purpose of Review Type 1 diabetes (T1D) is an autoimmune disease in which the
immune cells selectively destroy the pancreatic beta (β) cells and results in the deficiency of …

Two sides of the coin: cytoskeletal regulation of immune synapses in cancer and primary immune deficiencies

MB Saeed, J Record, LS Westerberg - International Review of Cell and …, 2020 - Elsevier
Actin cytoskeleton remodeling facilitates and fine-tunes diverse cellular processes. Cells
have evolved to use the same building blocks of actin monomers to form filaments through …

Molecular interactions between CTLA-4 and CD80/CD86 in the regulation of immune responses: a review article

Z Darvish Khalilabadi, A Raouf-Rahmati… - Medical Journal of …, 2024 - mjms.mums.ac.ir
One of the main mechanisms of regulating immune responses is the interaction between
CTLA-4 and CD80/CD86. CTLA-4 is an inhibitory receptor and has the same ligand as co …

برهمکنش های مولکولی بین CTLA-4 و CD80/CD86 در تنظیم پاسخ های ایمنی: مقاله مروری.

زهرا درویش خلیل آ, آمنه رئوف رحمتی… - Medical journal of …, 2024‎ - search.ebscohost.com
Introduction One of the main mechanisms of regulating immune responses is the interaction
between CTLA-4 and CD80/CD86. CTLA-4 is an inhibitory receptor and has the same …